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In this study, a simple, benign and efficient pathway was developed to synthesize 1,3\u2010diphenylpropan\u20101\u2010ols <jats:italic>via<\/jats:italic> the <jats:italic>\u03b2<\/jats:italic>\u2010alkylation of 1\u2010phenylethanol with benzyl alcohols. Unlike conventional borrowing hydrogen processes in which alcohols were activated by transition\u2010metal catalyzed dehydrogenation, in this work, <jats:italic>t\u2010<\/jats:italic>BuONa was suggested to be a dual\u2010role reagent, namely, both base and radical initiator, for the radical coupling of aromatic alcohols. The cross\u2010coupling reaction readily proceeded under transition metal\u2010free conditions and an inert atmosphere, affording 1,3\u2010diphenylpropan\u20101\u2010ol with an excellent yield. A good functional group tolerance in benzyl alcohols was observed, leading to the production of various phenyl\u2010substituted propan\u20101\u2010ol derivatives in moderate\u2010to\u2010good yields. The mechanistic studies proposed that the reaction could involve the formation of reactive radical anions by base\u2010mediated deprotonation and single electron transfer.<\/jats:p>","DOI":"10.1002\/open.202400139","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T16:04:58Z","timestamp":1724342698000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Green Synthesis of Diphenyl\u2010Substituted Alcohols <i>Via<\/i> Radical Coupling of Aromatic Alcohols Under Transition\u2010Metal\u2010Free Conditions"],"prefix":"10.1002","volume":"13","author":[{"given":"Ha V.","family":"Le","sequence":"first","affiliation":[{"name":"Faculty of Chemical Engineering Ho Chi Minh City University of Technology (HCMUT)  268 Ly Thuong Kiet 740010 District 10, Ho Chi Minh City Vietnam"},{"name":"Vietnam National University Ho Chi Minh City  Linh Trung Ward 720400 Thu Duc City, Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vy T. B.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering Ho Chi Minh City University of Technology (HCMUT)  268 Ly Thuong Kiet 740010 District 10, Ho Chi Minh City Vietnam"},{"name":"Vietnam National University Ho Chi Minh City  Linh Trung Ward 720400 Thu Duc City, Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huy X.","family":"Le","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering Ho Chi Minh City University of Technology (HCMUT)  268 Ly Thuong Kiet 740010 District 10, Ho Chi Minh City Vietnam"},{"name":"Vietnam National University Ho Chi Minh City  Linh Trung Ward 720400 Thu Duc City, Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tung T.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering Ho Chi Minh City University of Technology (HCMUT)  268 Ly Thuong Kiet 740010 District 10, Ho Chi Minh City Vietnam"},{"name":"Vietnam National University Ho Chi Minh City  Linh Trung Ward 720400 Thu Duc City, Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khoa D.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Faculty of Chemical Engineering Ho Chi Minh City University of Technology (HCMUT)  268 Ly Thuong Kiet 740010 District 10, Ho Chi Minh City Vietnam"},{"name":"Vietnam National University Ho Chi Minh City  Linh Trung Ward 720400 Thu Duc City, Ho Chi Minh City Vietnam"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8571-4114","authenticated-orcid":false,"given":"Phuoc H.","family":"Ho","sequence":"additional","affiliation":[{"name":"Chemical Engineering, Competence Centre for Catalysis Chalmers University of Technology  Gothenburg SE-412 96 Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thuong T. 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