{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:58:58Z","timestamp":1787878738344,"version":"build-2784847793"},"reference-count":56,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemistryOpen"],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:p>\n                    Iron oxide nanoparticles (IONPs) have emerged as the most widely synthesized metal nanoparticles in sustainable chemistry due to their unique magnetic properties, excellent biocompatibility, biodegradability, and non\u2010toxicity. In this study, IONPs are successfully synthesized via a rapid, sustainable, and environmentally friendly green synthesis approach using\n                    <jats:italic>Cannabis sativa<\/jats:italic>\n                    L. leaf extract. X\u2010ray diffraction analysis determined that the synthesized NPs had an average particle size of 18.8\u2009nm, while transmission electron microscopy images reveal a spherical morphology with sizes ranging from 12 to 21\u2009nm. Fourier\u2010transform infrared spectroscopy analysis confirmed the presence of cannabinoids, terpenoids, and flavonoids, which are believed to play a crucial role in the formation and stabilization of IONPs. Its photocatalytic potential is demonstrated through the degradation of bromophenol blue dye. Additionally, the NPs exhibited significant antibacterial and antifungal activity against various microbial species, along with promising anticancer effects on cancer cell lines. In conclusion, this study provides a promising foundation for advancing the large\u2010scale, commercial production of IONPs through green synthesis methods. By offering an eco\u2010friendly and efficient alternative to conventional nanoparticle synthesis, the findings contribute significantly to the growing body of research in sustainable nanotechnology.\n                  <\/jats:p>","DOI":"10.1002\/open.202500189","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T07:45:16Z","timestamp":1750146316000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Hemp\u2010Derived Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Characterization, and Therapeutic Potential"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7896-1042","authenticated-orcid":false,"given":"Nesrin","family":"Korkmaz","sequence":"first","affiliation":[{"name":"Department of Basic Sciences and Health Hemp Institute Yozgat Bozok University  Yozgat 66100 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6306-4760","authenticated-orcid":false,"given":"Rizvan","family":"\u0130mamo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology and Genetics Faculty of Sciences Bart\u0131n University  Bart\u0131n 74100 T\u00fcrkiye"},{"name":"Health Institutes of T\u00fcrkiye (TUSEB) T\u00fcrkiye Cancer Institute  \u0130stanbul 34718 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Karada\u011f","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Science and Letters Faculty Bursa Uluda\u011f University  Bursa 16059 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"\u015eahin Y\u0131ld\u0131r\u0131m","sequence":"additional","affiliation":[{"name":"\u0130mranl\u0131 Vocational School Department of Property Protection and Security Sivas Cumhuriyet University  Sivas 58140 T\u00fcrkiye"},{"name":"Health Services Vocational School Sivas Cumhuriyet University  Sivas 58140 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf","family":"Ceylan","sequence":"additional","affiliation":[{"name":"Health Institutes of T\u00fcrkiye (TUSEB) T\u00fcrkiye Cancer Institute  \u0130stanbul 34718 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6843-9026","authenticated-orcid":false,"given":"Fatih","family":"\u015een","sequence":"additional","affiliation":[{"name":"Sen Research Group Biochemistry Department Faculty of Arts and Science Dumlup\u0131nar University  Evliya \u00c7elebi Campus K\u00fctahya 43100 T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceja.2023.100471"},{"key":"e_1_2_9_3_1","first-page":"351","author":"Mallakpour S.","year":"2020","journal-title":"Process Chem. 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