{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T03:45:37Z","timestamp":1771299937084,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T00:00:00Z","timestamp":1757635200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemistryOpen"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:p>\n                    This study focuses on the ultrasonic synthesis of M\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    (M\u2009=\u2009Ag, Cu, Te &amp; Ta) nanoparticles (NPs) and screening of their cytotoxicity and antibacterial activities. The prepared NPs are characterized by different techniques such as X\u2010ray diffraction, transmission electron microscope, SEM\u2010EDX,DR\u2010UV\u2010visible spectrophotometer, and dynamic light scattering analysis. The cytotoxicity of M\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    nanoparticles are assessed against cancer cells such as colorectal carcinoma (HCT\u2010116) and cervical cancer cells (HeLa) and non\u2010cancer cells (embryonic kidney cells HEK\u2010293). The effect of post\u201048\u2009h treatment of CeO\n                    <jats:sub>2<\/jats:sub>\n                    , Ag\u2010CeO\n                    <jats:sub>2,<\/jats:sub>\n                    Cu\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    , Te\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    , and Ta\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    , on HCT\u2010116 and HeLa cells showed a noteworthy reduction in cell viability. The treatments of Ag\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    also display a reduction in cancer cell viability but statistically not significant. The treatment of CeO\n                    <jats:sub>2<\/jats:sub>\n                    shows better inhibitory action on HCT\u2010116 and HeLa cells. HEK\u2010293 is treated with CeO\n                    <jats:sub>2,<\/jats:sub>\n                    Ag\u2010CeO\n                    <jats:sub>2,<\/jats:sub>\n                    Cu\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    , Te\u2010CeO\n                    <jats:sub>2,<\/jats:sub>\n                    and Ta\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    NPs with the same dosages, there is a minor decline in the cell number, but the percentage of cells viability is greater than HCT\u2010116 and HeLa cells. The antibacterial activity of NPs against\n                    <jats:italic>E. coli<\/jats:italic>\n                    and\n                    <jats:italic>S. aureus<\/jats:italic>\n                    is tested, and Te\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    NPs show better antibacterial activity. The lowest MIC displayed by Te\u2010CeO\n                    <jats:sub>2<\/jats:sub>\n                    is 0.25 mg\u2009mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    against\n                    <jats:italic>E. coli<\/jats:italic>\n                    and 4 mg\u2009mL\n                    <jats:sup>\u22121<\/jats:sup>\n                    for\n                    <jats:italic>S. aureus<\/jats:italic>\n                    , respectively.\n                  <\/jats:p>","DOI":"10.1002\/open.202500278","type":"journal-article","created":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T07:36:32Z","timestamp":1757662592000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Exploration of Cytotoxicity and Antibacterial Activities of M\u2010Ceo\n                    <sub>2<\/sub>\n                    (M = Ag, Cu, Te, and Ta) Nanoparticles"],"prefix":"10.1002","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5273-583X","authenticated-orcid":false,"given":"Faiza","family":"Qureshi","sequence":"first","affiliation":[{"name":"Deanship of Scientific Research Imam Abdulrahman Bin Faisal University  P.O. Box 1982 Dammam 31441 Saudi Arabia"},{"name":"Department of Nano\u2010Medicine Research Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suhailah S.","family":"Aljameel","sequence":"additional","affiliation":[{"name":"Department of Chemistry College of Science Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9016-9229","authenticated-orcid":false,"given":"Muhammad","family":"Nawaz","sequence":"additional","affiliation":[{"name":"Department of Nano\u2010Medicine Research Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Azam","family":"Ansari","sequence":"additional","affiliation":[{"name":"Department of Epidemic Diseases Research Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  P.O. Box 1982 Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Firdos Alam","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Stem Cell Research Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  P.O. Box 1982 Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sultan","family":"Akhtar","sequence":"additional","affiliation":[{"name":"Department of Biophysics Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariam Ali","family":"Alsayed","sequence":"additional","affiliation":[{"name":"Department of Nano\u2010Medicine Research Institute for Research and Medical Consultations (IRMC) Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad J.","family":"Akbar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics College of Pharmacy Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"family":"Muzaheed","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory Science College of Applied Medical Sciences Imam Abdulrahman Bin Faisal University  Dammam 31441 Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231911403"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apt.2024.104654"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mseb.2024.117777"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28073086"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2019.111723"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2021.132288"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0204061"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094777"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2NJ01352E"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219665110"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn304332s"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2011.01.002"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/nl204203t"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2024.113822"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2EN00210H"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym13060924"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26175416"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.22291"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stress.2021.100006"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/plants13202934"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.inoche.2022.109976"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S62057"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1039\/b922024k"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn100816s"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-3163-5-14"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S255784"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aquatox.2014.03.027"},{"key":"e_1_2_9_29_1","first-page":"5515","volume":"9","author":"Babu K. 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