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This approach offers numerous advantages, including high isolated yields (86\u201399%) and short reaction times (10\u201370 min), along with broad substrate compatibility for both electron\u2010donating and electron\u2010withdrawing functional groups. The method exhibits excellent catalytic efficiency, with high turnover numbers and turnover frequencies, even at low catalyst loading. The use of ChCl\u2013Urea as a green, biodegradable, and nonvolatile solvent aligns with sustainable chemistry principles and allows for easy solvent recovery. Additionally, the magnetic nanocatalyst is easily recoverable and reusable, maintaining activity over multiple cycles. Operational simplicity, mild conditions, and one\u2010pot multi\u2010component reaction design further enhance the method's scalability and synthetic utility. Given the biological relevance of benzopyrano\u2010pyrimidines, this strategy presents a valuable platform for green synthesis in medicinal chemistry and pharmaceutical development.<\/jats:p>","DOI":"10.1002\/open.202500398","type":"journal-article","created":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T06:40:53Z","timestamp":1757745653000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["A Robust Nanocatalyst Incorporating Multi\u2010Walled Carbon Nanotubes Infused with Magnetic Nanoparticles and Biguanide\u2013Silver Nanoparticles for Multicomponent Synthesis of Benzopyrano\u2010Pyrimidines"],"prefix":"10.1002","volume":"14","author":[{"given":"Anwer Ali","family":"Mueen","sequence":"first","affiliation":[{"name":"College of Dentistry Department of Basic Sciences Al\u2010Qadisiyah University  Al\u2010Qadisiyah Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suranjana V.","family":"Mayani","sequence":"additional","affiliation":[{"name":"Marwadi University Research Center Department of Chemistry Faculty of Science Marwadi University  Rajkot Gujarat India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suhas","family":"Ballal","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry School of Sciences JAIN (Deemed to be University)  Bangalore Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaker","family":"Al\u2010Hasnaawei","sequence":"additional","affiliation":[{"name":"College of Pharmacy the Islamic University  Najaf Iraq"},{"name":"Department of medical analysis Medical laboratory technique college the Islamic University of Al Diwaniyah  Al Diwaniyah Iraq"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhayveer","family":"Singh","sequence":"additional","affiliation":[{"name":"Centre for Research Impact &amp; Outcome Chitkara University Institute of Engineering and Technology Chitkara University  Rajpura Punjab 140401 India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kattela","family":"Chennakesavulu","sequence":"additional","affiliation":[{"name":"Department of Chemistry Sathyabama Institute of Science and Technology  Chennai Tamil Nadu India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamal Kant","family":"Joshi","sequence":"additional","affiliation":[{"name":"Department of Allied Science Graphic Era Hill University  Dehradun India"},{"name":"Adjunct Professor Graphic Era Deemed to be University  Dehradun Uttarakhand India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-0838-4509","authenticated-orcid":false,"given":"Reza","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Department of Chemistry Young Researchers and Elite Club Tehran Branch Islamic Azad University  Tehran Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s42823-024-00835-w"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-55372-4_9"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4CS00492B"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1515\/ntrev-2017-0138"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA08733G"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1556-276X-6-303"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rinp.2017.10.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1088\/1757-899X\/202\/1\/012013"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10562-024-04912-7"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/aoc.4018"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm301402g"},{"key":"e_1_2_8_13_1","first-page":"120","volume":"1","author":"Mustafa A. 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