{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:55:51Z","timestamp":1790668551686,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemistryOpen"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>Low molecular weight gels are versatile materials prized for their ease of modification compared to their polymeric counterparts, which facilitate their valorization into task\u2010specific materials. However, such modifications seldom extend beyond mere functionalization, and strategies for transferring privileged gelator scaffolds between hydrophilic and lipophilic environments remain rare. In this work, we present a general approach for the late\u2010stage polarity swap (LSPS) of the lipophilic, highly modular oxotriphenylhexanoate (OTHO) scaffold after functionalization with the fluorescent probe 9,10\u2010diphenylanthracene (DPA). The compounds obtained were tested for gelation under different conditions, with the resulting hydrogels characterized by oscillatory rheology. SEM images of the xerogels reveal fibrillar assemblies, demonstrating the self\u2010assembling capabilities of OTHOs remain unaffected regardless of medium.<\/jats:p>","DOI":"10.1002\/open.70309","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T05:24:36Z","timestamp":1790227476000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcending Lipophilicity: Design of Oxotriphenylhexanoate (OTHO) Hydrogels Decorated With 9,10\u2010Diphenylanthracene Fluorescent Probes via Late\u2010Stage Polarity Swap"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-0366-3078","authenticated-orcid":false,"given":"Michel","family":"Taheri","sequence":"first","affiliation":[{"name":"Department of Chemistry and Molecular Biology University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7057-9618","authenticated-orcid":false,"given":"Mario","family":"Martos","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Molecular Biology University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-9748-8884","authenticated-orcid":false,"given":"Olivia","family":"Lundgren","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Molecular Biology University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6202-7557","authenticated-orcid":false,"given":"Henrik","family":"Sund\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Molecular Biology University of Gothenburg  Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chempr.2017.07.012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3SM01301D"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202015703"},{"key":"e_1_2_8_5_1","first-page":"233","volume-title":"Supramolecular Science Where It Is and Where It Is Going","author":"Van Esch J.","year":"1999"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00299"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.1c01914"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5TA08010J"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.12.019"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2023.122023"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.9b03846"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202200205"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201800635"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201404288"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1063\/5.0029307"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC08994B"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.3c02091"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202400827"},{"key":"e_1_2_8_19_1","doi-asserted-by":"crossref","unstructured":"S. C.Zacharias M.Martos A.Runemark M.Rander andH.Sund\u00e9n \u201cExploring the Influence of Substitution in the Gelation Characteristics of Oxotriphenylhexanoates (OTHOs) \u201d ChemRxiv preprint (2026) https:\/\/doi.org\/10.26434\/chemrxiv.10001992\/v1.","DOI":"10.26434\/chemrxiv.10001992\/v1"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5CS00136F"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.02.086"}],"container-title":["ChemistryOpen"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/open.70309","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/open.70309","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/open.70309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:09:39Z","timestamp":1790665779000},"score":1,"resource":{"primary":{"URL":"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/10.1002\/open.70309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/open.70309"],"URL":"https:\/\/doi.org\/10.1002\/open.70309","archive":["Portico"],"relation":{},"ISSN":["2191-1363","2191-1363"],"issn-type":[{"value":"2191-1363","type":"print"},{"value":"2191-1363","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]},"assertion":[{"value":"2026-09-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70309"}}