{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:59:21Z","timestamp":1790837961177,"version":"4.1.0"},"reference-count":112,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:00:00Z","timestamp":1790726400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["chemistry-europe.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["ChemistryOpen"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:p>\n                    Four Schiff bases newly synthesized from 2\u2010chloro\u20105\u2010(trifluoromethyl)aniline served as ligands for the preparation of four palladium(II) complexes. Characterization of all compounds was performed using the following physicochemical techniques: elemental analysis, IR, UV\u2013vis,\n                    <jats:sup>1<\/jats:sup>\n                    H NMR,\n                    <jats:sup>13<\/jats:sup>\n                    C NMR, mass spectrometry, thermal analysis, molar conductivity, and magnetic susceptibility. In addition, crystals of the ligands\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>1<\/jats:bold>\n                    <\/jats:sup>\n                    \u2013\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>4<\/jats:bold>\n                    <\/jats:sup>\n                    and the complexes\n                    <jats:bold>2<\/jats:bold>\n                    and\n                    <jats:bold>4<\/jats:bold>\n                    were obtained, enabling their structures to be confirmed by single\u2010crystal X\u2010ray diffraction. Crystallography showed that ligands form molecular crystals with one molecule per unit cell, except\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>1<\/jats:bold>\n                    <\/jats:sup>\n                    , which contains two chemically identical molecules;\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>1<\/jats:bold>\n                    <\/jats:sup>\n                    ,\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>2<\/jats:bold>\n                    <\/jats:sup>\n                    , and\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>4<\/jats:bold>\n                    <\/jats:sup>\n                    are centrosymmetric, and\n                    <jats:bold>HL<\/jats:bold>\n                    <jats:sup>\n                      <jats:bold>3<\/jats:bold>\n                    <\/jats:sup>\n                    crystallizes as a pure enantiomer. Complex\n                    <jats:bold>4<\/jats:bold>\n                    is mononuclear, coordinated by two deprotonated ligands through an N\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    donor set, while complex\n                    <jats:bold>2<\/jats:bold>\n                    is dinuclear, with each palladium(II) coordinated via an O\n                    <jats:sub>3<\/jats:sub>\n                    N set by one bidentate anionic ligand and two bidentate\u2010bridging acetate anions. Phytotoxicity and animal toxicity were assessed using\n                    <jats:italic>Triticum aestivum<\/jats:italic>\n                    L. and\n                    <jats:italic>Artemia franciscana<\/jats:italic>\n                    Kellogg, respectively. Complexes were slightly more inhibitory than ligands on\n                    <jats:italic>Triticum<\/jats:italic>\n                    , but overall effects were weak, with root growth exceeding that of the negative control at all tested concentrations. Only complexes\n                    <jats:bold>2<\/jats:bold>\n                    and\n                    <jats:bold>4<\/jats:bold>\n                    exhibited dose\u2010dependent toxicity in\n                    <jats:italic>Artemia<\/jats:italic>\n                    , with LC\n                    <jats:sub>50<\/jats:sub>\n                    values of 389.8 and 48.7\u2009\u00b5M.\n                  <\/jats:p>","DOI":"10.1002\/open.70315","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:42:03Z","timestamp":1790836923000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["2\u2010Chloro\u20105\u2010(trifluoromethyl)aniline\u2010Derived Schiff Base Palladium(II) Complexes: From Molecular Design to Acute Toxicity Assessment"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4649-8496","authenticated-orcid":false,"given":"Andreea 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