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This study investigated the age\u2010specific association of body mass index and waist circumference with metabolic diseases, assessing their applicability as diagnostic criteria for individuals aged \u226565\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Analysis included 46,324 individuals aged \u226518\u00a0years, categorized into five age groups: 18\u201344, 45\u201354, 55\u201364, 65\u201374, and \u226575\u00a0years. Logistic regression analyses identified associations between obesity and metabolic diseases, stratified by age and sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Men with obesity based on body mass index had a significantly high risk of hypertension, diabetes mellitus, and dyslipidemia across all age groups (all, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). Obesity based on waist circumference was significantly positively associated with all metabolic diseases (all, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05). Women with obesity based on body mass index and waist circumference had a significantly high risk of all metabolic diseases across all age groups (all, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05), except for diabetes mellitus in individuals aged \u226575\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Participants with obesity based on body mass index and waist circumference exhibited a high risk of hypertension, diabetes mellitus, and dyslipidemia among those aged 18\u201374\u00a0years and men aged \u226575\u00a0years. This study contributes to the early prevention and control of metabolic diseases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/osp4.746","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T15:08:20Z","timestamp":1710774500000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Age\u2010wise examination of the association of obesity based on body mass index and waist circumference with metabolic diseases in comprehensive health checkup participants"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-6045-1444","authenticated-orcid":false,"given":"Yuiko","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Graduate School of Health and Sports Science Doshisha University  Kyotanabe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Ikeue","sequence":"additional","affiliation":[{"name":"Graduate School of Health and Sports Science Doshisha University  Kyotanabe Japan"},{"name":"Department of Endocrinology, Metabolism, and Hypertension Research Clinical Research Institute National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megumi","family":"Kanasaki","sequence":"additional","affiliation":[{"name":"Medical Examination Center Takeda Hospital  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Yamakage","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolism, and Hypertension Research Clinical Research Institute National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Satoh\u2010Asahara","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolism, and Hypertension Research Clinical Research Institute National Hospital Organization Kyoto Medical Center  Kyoto Japan"},{"name":"Department of Molecular Medicine and Metabolism Research Institute of Environmental Medicine Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Izuru","family":"Masuda","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Metabolism, and Hypertension Research Clinical Research Institute National Hospital Organization Kyoto Medical Center  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kojiro","family":"Ishii","sequence":"additional","affiliation":[{"name":"Faculty of Health and Sports Science Doshisha University  Kyotanabe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,3,18]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.66.987"},{"key":"e_1_2_9_3_1","volume-title":"Guidelines for the Management of Obesity Disease 2022","author":"Japan Society for the Study of Obesity","year":"2022"},{"key":"e_1_2_9_4_1","first-page":"464","article-title":"Guidelines for the management of obesity disease in the elderly 2018","volume":"55","author":"The Japan Geriatrics Society: working group for the development of \u201cGuidelines for the Management of Lifestyle\u2010related Diseases in the elderly\u201d","year":"2018","journal-title":"Jpn J Geriatr"},{"issue":"1","key":"e_1_2_9_5_1","first-page":"1","article-title":"Ideal body weight estimated from the body mass index with the lowest morbidity","volume":"15","author":"Tokunaga K","year":"1991","journal-title":"Int J Obes"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2010.03.006"},{"key":"e_1_2_9_7_1","unstructured":"Ministry of Health Labour and Welfare.The Standard Specific Health Checkups and Specific Health Guidance Program;2018. 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