{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:50:57Z","timestamp":1760986257678,"version":"build-2065373602"},"reference-count":29,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":58,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The aim of this study is to evaluate the association between race and the treatment of laryngeal dysplasia and early\u2010stage laryngeal squamous cell carcinoma (LSCC).<\/jats:p><\/jats:sec><jats:sec><jats:title>Study design<\/jats:title><jats:p>Retrospective Cohort Study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Large multispecialty academic medical center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were treated for laryngeal dysplasia or LSCC between September 2019 and September 2022. A retrospective chart review was conducted to collect demographic and clinical information. Two\u2010sample <jats:italic>t<\/jats:italic> tests, chi\u2010square tests, and linear regression models were used to compare characteristics (<jats:italic>\u03b1<\/jats:italic>\u2009=\u20090.05). Analyses were performed in STATA 17.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010five\u00a0patients were identified that underwent potassium titanyl phosphate (KTP) transoral laser microsurgery for management of early\u2010stage LSCC (n\u2009=\u200929) or dysplasia (n\u2009=\u200936). The cohort consisted of 23 Black and 42 White patients. No significant difference was found in age, alcohol or tobacco use, rate of adjuvant radiotherapy, stage of disease, nor insurance status between the 2 groups. White patients underwent more procedures to address initial disease and subsequent recurrent dysplasia on average than Black patients (2.52 vs 1.52, <jats:italic>P<\/jats:italic>\u2009=\u2009.02). This remained true after adjusting for demographic and clinical characteristics and insurance status in a linear regression model. While Black patients were more likely to be lost to follow\u2010up than White patients (30.4% vs 9.5%, <jats:italic>P<\/jats:italic>\u2009=\u2009.03), the average number of procedures between the groups still differed significantly (2.63 vs 1.56, <jats:italic>P<\/jats:italic>\u2009=\u2009.04) when controlling for those lost to follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The findings presented here highlight potential inequities that exist for racial minorities at early stages of treatment and in addressing premalignant conditions, which may contribute to the known downstream disparities in laryngeal cancer outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oto2.119","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T07:59:35Z","timestamp":1709107175000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Racial Disparities in Surgical Management For Early\u2010Stage Laryngeal Squamous Cell Carcinoma and Recurrent Dysplasia"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5774-3241","authenticated-orcid":false,"given":"Thomas F.","family":"Cyberski","sequence":"first","affiliation":[{"name":"Pritzker School of Medicine The University of Chicago Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander Z.","family":"Wang","sequence":"additional","affiliation":[{"name":"Pritzker School of Medicine The University of Chicago Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brandon J.","family":"Baird","sequence":"additional","affiliation":[{"name":"Section of Otolaryngology\u2013Head and Neck Surgery, Department of Surgery The University of Chicago Medicine Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"American Cancer Society.Cancer Facts & Figures 2023.American Cancer Society; 2023."},{"issue":"4","key":"e_1_2_8_3_1","first-page":"367","article-title":"Clinical, histological and immunohistochemical evaluation of larynx cancer","volume":"43","author":"Ciolofan MS","year":"2017","journal-title":"Curr Health Sci J"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0149886"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2011.01.013"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29171"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01538-3"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25212"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2011.171"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2015.10.004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29046"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2015.48"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.133.12.1198"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-019-0367-2"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-021-00881-w"},{"key":"e_1_2_8_16_1","unstructured":"Race and National Origin. 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