{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:23:49Z","timestamp":1760955829914,"version":"build-2065373602"},"reference-count":52,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T00:00:00Z","timestamp":1720137600000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To use pharyngeal pressure recordings to distinguish different upper airway collapse patterns in obstructive sleep apnea (OSA) patients, and to assess whether these pressure recordings correlate with candidacy assessment for hypoglossal nerve stimulator (HGNS) implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>Prospective case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Single tertiary\u2010quaternary care academic center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Subjects with OSA prospectively underwent simultaneous drug\u2010induced sleep endoscopy (DISE) and transnasal pharyngeal pressure recording with a pressure\u2010transducing catheter. Pressure was recorded in the nasopharynx and oropharynx, and endoscopic collapse patterns were classified based on site, extent, and direction of collapse. Pressure recordings were classified categorically by waveform shape as well as numerically by inspiratory and expiratory amplitudes and slopes. Waveform shape, amplitude, and slope were then compared with the endoscopic findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010five subjects with OSA were included. Nasopharyngeal waveform shape was associated with the extent of collapse at the level of the palate (<jats:italic>P<\/jats:italic>\u2009=\u2009.001). Oropharyngeal waveform shape was associated with anatomical site of collapse (<jats:italic>P<\/jats:italic>\u2009&lt;\u2009.001) and direction of collapse (<jats:italic>P<\/jats:italic>\u2009=\u2009.019) below the level of the palate. Pressure amplitudes and slopes were also associated with the extent of collapse at various sites. Waveform shape was also associated with favorable collapse pattern on endoscopy for HGNS implantation (<jats:italic>P<\/jats:italic>\u2009=\u2009.043), as well as surgical candidacy for HGNS (<jats:italic>P<\/jats:italic>\u2009=\u2009.004).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Characteristic pharyngeal pressure waveforms are associated with different airway collapse patterns. Pharyngeal pressure is a promising adjunct to DISE in the sleep surgery candidacy evaluation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oto2.161","type":"journal-article","created":{"date-parts":[[2024,7,5]],"date-time":"2024-07-05T07:54:56Z","timestamp":1720166096000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Characteristic Pressure Waveforms Can Distinguish Airway Collapse Patterns in Sleep Apnea Patients: A Pilot Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8554-4338","authenticated-orcid":false,"given":"Ravi R.","family":"Shah","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Henry Ford Health + Michigan State University Detroit Michigan USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad F.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Summit Medical Group Berkeley Heights New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raj C.","family":"Dedhia","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery University of Pennsylvania Philadelphia Pennsylvania USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erica R.","family":"Thaler","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery University of Pennsylvania Philadelphia Pennsylvania 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