{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T03:00:03Z","timestamp":1775271603291,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T00:00:00Z","timestamp":1721520000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Chronic subjective tinnitus is a worldwide intractable problem. In our previous studies, customized music therapy combined with a follow\u2010up system can reduce tinnitus perception and improve anxiety\/depression. This study aims to explore which characteristics of tinnitus patients are more likely to benefit from our therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Study Design<\/jats:title><jats:p>This study included 1031 patients with chronic subjective tinnitus, all of whom completed customized music therapy with the follow\u2010up system. Population demographics, tinnitus characteristics, and tinnitus\u2010related scales at pretherapy and posttherapy were collected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Huadong Hospital affiliated Fudan University, Department of Otorhinolaryngology\u2013Head &amp; Neck Surgery from 2018 to 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A paired <jats:italic>t<\/jats:italic> test and the one\u2010way analysis of variance were utilized to the overall efficacy and stratified difference based on tinnitus duration\/age\/tinnitus frequency.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were significant statistical differences in the Tinnitus Handicap Inventory (THI), Tinnitus Loudness Visual Analog Scale (VAS), and Hospital Anxiety and Depression Scale (HADS)\u2010A\/D scores between pretherapy and 3 months posttherapy. THI and HADS (A\/D) scores decreased the most in the 1\u2010year duration tinnitus group. The most significant decrease in THI and VAS scores was observed in the 31\u2010 to 50\u2010year\u2010old tinnitus group. Patients with high\u2010frequency tinnitus and extended high\u2010frequency tinnitus had greater decreases generally than those with low\u2010frequency tinnitus though no significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Group with severe and prolonged tinnitus, shorter duration of tinnitus onset, and 31 to 50 years old benefit more from our therapy. Therefore, standardized personalized music and consulting and follow\u2010up systems while promoting early treatment can reduce tinnitus and its comorbidities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oto2.173","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T10:40:01Z","timestamp":1721558401000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Customized Music Therapy Combined With the Counseling and Follow\u2010Up System: Stratified Results for Tinnitus Efficacy"],"prefix":"10.1002","volume":"8","author":[{"given":"Tianyi","family":"Ni","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuehong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongbo","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siyi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yulu","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yun","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5753-6952","authenticated-orcid":false,"given":"Zhao","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery Huadong Hospital Affiliated Fudan University  Shanghai China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,21]]},"reference":[{"issue":"11","key":"e_1_2_10_2_1","article-title":"Ginkgo biloba for tinnitus","volume":"11","author":"Sereda M","year":"2022","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-019-0633-7"},{"issue":"5","key":"e_1_2_10_4_1","first-page":"325","article-title":"[Diagnosis and treatment of tinnitus]","volume":"36","author":"Yu L","year":"2022","journal-title":"Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2021.1909760"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2009.07.013"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2016.00370"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2021.1922754"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1044\/2022_AJA-22-00127"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1044\/2021_JSLHR-21-00210"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-023-00631-y"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1044\/2022_AJA-21-00170"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2016.1265154"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1044\/2021_AJA-20-00164"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1080\/14992027.2018.1537524"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2008.11.036"},{"key":"e_1_2_10_17_1","first-page":"1","article-title":"Why is tinnitus a problem? 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