{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T04:03:21Z","timestamp":1772165001671,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T00:00:00Z","timestamp":1721779200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2024,7]]},"abstract":"Abstract<\/jats:title>Meniere's disease (MD) is a complex inner ear disease related to endolymphatic hydrops and with multiple other etiologies suggested including autoimmunity and vascular insufficiency. Statins are lipid\u2010lowering medications with additional effects including reduction of oxidative stress and inflammation. We performed a cross\u2010sectional study comparing patients with MD on statins to those not on statins to see if there is any difference in disease activity (major vertigo spells) and hearing stage utilizing linear and logistic regression. Our analysis showed no difference in the average number of major vertigo spells per month (\u03b2<\/jats:italic>\u2009=\u2009.07, P<\/jats:italic>\u2009=\u2009.9) between statin users and nonusers; however, statin users were found to have lower odds of worse hearing (odds ratio\u2009=\u20090.46, P<\/jats:italic>\u2009=\u2009.047). Further studies are needed to confirm our results.<\/jats:p>","DOI":"10.1002\/oto2.177","type":"journal-article","created":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T02:00:21Z","timestamp":1721872821000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Meniere's Disease and Statins: Is There an Association? A Single Institution Study"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1148-1896","authenticated-orcid":false,"given":"Mustafa G.","family":"Bulbul","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery West Virginia University Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tyler","family":"Wanstreet","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery West Virginia University Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amani","family":"Kais","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery West Virginia University Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garrett H.","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery West Virginia University Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7089-4658","authenticated-orcid":false,"given":"Brian M.","family":"Kellermeyer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery West Virginia University Morgantown West Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,24]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2010.05.001"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000286213"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200111000-00030"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2841-1"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2016.28"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13457"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18168692"},{"issue":"6","key":"e_1_2_8_9_1","first-page":"631","article-title":"Statin therapy: review of safety and potential side effects","volume":"32","author":"Ramkumar S","year":"2016","journal-title":"Acta Cardiol Sin"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-12-114"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.15171\/ijoem.2016.627"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820909438"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20130332"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-7568(23)00232-5"}],"container-title":["OTO Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oto2.177","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T09:20:29Z","timestamp":1760952029000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/oto2.177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/oto2.177"],"URL":"https:\/\/doi.org\/10.1002\/oto2.177","archive":["Portico"],"relation":{},"ISSN":["2473-974X","2473-974X"],"issn-type":[{"value":"2473-974X","type":"print"},{"value":"2473-974X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-04-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e177"}}