{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T15:36:42Z","timestamp":1783093002880,"version":"3.54.6"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T00:00:00Z","timestamp":1737244800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>The objective of this study is to determine the effectiveness and safety profile of coblation tongue base reduction (CBTR) compared to radiofrequency base of tongue (RFBOT) reduction on sleep\u2010related outcomes in patients with obstructive sleep apnea (OSA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Data Sources<\/jats:title><jats:p>PubMed, Scopus, Web of Science, and Cochrane Database of Systematic Reviews databases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Review Methods<\/jats:title><jats:p>Literature search by 2 independent authors was conducted using the abovementioned databases. Studies on CBTR and RFBOT as part of OSA treatment in adult patients with pre\u2010 and postoperative apnea\u2013hypopnea index (AHI) were included. Direct meta\u2010analysis and single\u2010arm meta\u2010analysis were conducted to compare sleep\u2010related outcomes (AHI, apnea index [AI], surgical success rates, Epworth sleepiness score [ESS], SpO<jats:sub>2<\/jats:sub>, body mass index [BMI], and visual analog scale [VAS]) between both groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 40 studies with a total of 1940 patients were included, of which 1440 individuals who underwent tongue base reduction interventions (RF\u2009=\u2009306, RF\u2009+\u2009UPPP\u2009=\u2009656, and coblation\u2009+\u2009UPPP\u2009=\u2009482) met inclusion criteria. Pooled analysis showed significant improvements in AHI (CBTR\u2009=\u2009\u221222.84, RFBOT\u2009=\u2009\u221211.14), AI (CBTR\u2009=\u200915.64, RFBOT\u2009=\u2009\u22125.26), ESS (CBTR\u2009=\u2009\u22127.59, RFBOT\u2009=\u2009\u22127.18), mean oxygen saturation (CBTR\u2009=\u20097.43, RFBOT\u2009=\u20094.25), mean BMI (CBTR\u2009=\u2009\u22120.69, RFBOT\u2009=\u2009\u22124.09), and snoring visual analog scale (CBTR\u2009=\u2009\u221216.20, RFBOT\u2009=\u2009\u221218.21). Surgical success rate (postoperative AHI\u2009&lt;\u200920 and drop &gt;50% from baselines) was 70% for CBTR and 43% for RFBOT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Both interventions decreased sleep\u2010related outcomes in adult patients with OSA. Coblation appears to exhibit superiority over radiofrequency with a similar safety profile. However, further studies with direct comparisons between both interventions must be performed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/oto2.70076","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T01:53:53Z","timestamp":1737338033000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Coblation Versus Radiofrequency for Tongue Base Reduction in Obstructive Sleep Apnea: A Meta\u2010analysis"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7287-7694","authenticated-orcid":false,"given":"Salman","family":"Hussain","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Ottawa Ottawa Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jafar","family":"Hayat","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Jaber 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