{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:40:25Z","timestamp":1791690025576,"version":"4.3.4"},"reference-count":11,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T00:00:00Z","timestamp":1779408000000},"content-version":"vor","delay-in-days":51,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Acoustic resonance therapy (ART), in which individually calibrated acoustic vibratory energy is delivered to the sinonasal cavities, has been shown to be safe and efficacious to reduce symptoms in adults with allergic and\/or nonallergic rhinitis. This prospective, nonrandomized, single\u2010center feasibility study evaluated potential use in pediatric patients age 12 to 21 with a nasal congestion sub\u2010score of \u22652 out of 3 on the Total Nasal Symptom Score (TNSS). Nasal congestion sub\u2010score at baseline was compared with an average of the daily score obtained over 2 weeks on treatment. 31 subjects enrolled. Nasal congestion sub\u2010score changed by \u22120.76 (95% CI [\u22120.97, \u22120.54],\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001) for an average reduction of 35.2%, while aggregate TNSS changed by \u22122.74 (95% CI [\u22123.41, \u22122.06],\n                    <jats:italic>P<\/jats:italic>\n                    \u2009&lt;\u2009.0001) for an average reduction of 40.5%. All other TNSS subcomponents demonstrated statistically significant improvements compared with their respective baseline. ART warrants further investigation as a nonpharmacologic option for treatment of pediatric chronic rhinitis.\n                  <\/jats:p>","DOI":"10.1002\/oto2.70247","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T12:36:47Z","timestamp":1779453407000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Acoustic Vibrational Therapy for the Treatment of Pediatric Rhinitis"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9960-7758","authenticated-orcid":false,"given":"Ashoke R.","family":"Khanwalkar","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Colorado Anschutz School of Medicine Aurora Colorado USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Greene","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paramesh","family":"Gopi","sequence":"additional","affiliation":[{"name":"SoundHealth Los Altos California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Mohan","sequence":"additional","affiliation":[{"name":"SoundHealth Los Altos California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryant","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medicine Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery Stanford University School of Medicine Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.2022-005618"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-023-00670-0"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22877"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23284"},{"issue":"1","key":"e_1_2_7_6_1","first-page":"1","article-title":"Long\u2010term efficacy of HDM\u2010SCIT in pediatric and adult patients with allergic rhinitis","volume":"19","author":"Ren L","year":"2023","journal-title":"Allergy Asthma Clin Immunol [Internet]"},{"key":"e_1_2_7_7_1","unstructured":"MeliadisC JohnsonJ ZhuW. 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The Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBS) IEEE; 2023."},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2217\/bmm.13.11"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/falgy.2025.1649031"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.21873\/invivo.12052"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)60477-2"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.02.006"}],"container-title":["OTO Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oto2.70247","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/oto2.70247","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oto2.70247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:11:32Z","timestamp":1787760692000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/oto2.70247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/oto2.70247"],"URL":"https:\/\/doi.org\/10.1002\/oto2.70247","archive":["Portico"],"relation":{},"ISSN":["2473-974X","2473-974X"],"issn-type":[{"value":"2473-974X","type":"print"},{"value":"2473-974X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2026-01-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70247"}}