{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:34:16Z","timestamp":1787762056914,"version":"build-2784847793"},"reference-count":43,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T00:00:00Z","timestamp":1778803200000},"content-version":"vor","delay-in-days":44,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the long\u2010term impact of temperature\u2010controlled radiofrequency (TCRF) treatment on sleep\u2010related symptoms in patients with nasal airway obstruction (NAO), including those with documented obstructive sleep apnea (OSA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Pooled analysis of prospective multicenter studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Seven academic and 25 private otolaryngology sites.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A pooled analysis of 345 adults across four prospective multicenter studies (PIVOTAL, VATRAC, SWELL, and AERWAY) from 7 academic and 25 private otolaryngology sites was conducted. Participants had severe\u2010to\u2010extreme NAO and received a single, office\u2010based TCRF treatment targeting the nasal valve or septal swell body (SSB). Outcomes included sleep\u2010related components of the Nasal Obstruction Symptom Evaluation (NOSE) scale, 22\u2010item Sino\u2010Nasal Outcome Test (SNOT\u201022) sleep domain, and Epworth Sleepiness Scale (ESS). Analyses included stratification by the presence or absence of OSA and linear regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>TCRF treatment was associated with significant, durable improvements in sleep\u2010related symptoms through 24 months. At 24 months, the \u201cTrouble Sleeping\u201d subcomponent of the NOSE score improved by \u22121.9 (95% CI, \u22122.0 to \u22121.7) points, a 64% improvement. SNOT\u201022 sleep domain scores declined by \u22129.0 (95% CI, \u221210.5 to \u22127.6) points, with more than 80% of participants achieving clinical improvement. Among those with excessive daytime sleepiness (ESS\u2009\u2265\u200910), ESS dropped by \u22128.3 (95% CI, \u22129.7 to \u22126.9), and the prevalence of sleepiness fell from 53.8% to 9.8%. Improvements were consistent across the OSA+ subgroup.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Office\u2010based TCRF therapy targeting the nasal valve and\/or SSB is associated with clinically meaningful, durable improvements in sleep\u2010related symptoms and daytime somnolence in NAO patients, including a subset of those with documented OSA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oto2.70250","type":"journal-article","created":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:20:48Z","timestamp":1778876448000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pooled Analysis of Sleep Outcomes After Treatment With Temperature\u2010Controlled Radiofrequency in Nasal Airway Obstruction Patients"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9790-3529","authenticated-orcid":false,"given":"Masayoshi","family":"Takashima","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head &amp; Neck Surgery Houston Methodist Hospital Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwin","family":"Ananth","sequence":"additional","affiliation":[{"name":"Eastern Shore ENT Fairhope Alabama USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul T.","family":"Hoff","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Michigan Medical School Ann Arbor Michigan USA"},{"name":"Michigan Otolaryngology Surgery Associates Ypsilanti Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul Schalch","family":"Lepe","sequence":"additional","affiliation":[{"name":"Silenso Clinic San Diego California USA"},{"name":"Departments of Otolaryngology\u2013Head and Neck Surgery and Sleep Medicine UC San Diego Health San Diego California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Setzen","sequence":"additional","affiliation":[{"name":"Albany ENT and Allergy Services, P.C. Albany New York USA"},{"name":"Department of Otolaryngology Albany Medical College Albany New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria V.","family":"Suurna","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery University of Miami Health System Miami Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2023.11.002"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-2173"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/life12020305"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-018-00193-1"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.17465"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23079"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.4886"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(97)70124-6"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-019-01607-z"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/717419"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00050208"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2010.04.019"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29509"},{"key":"e_1_2_10_15_1","first-page":"1","article-title":"The causes of persistent and recurrent nasal obstruction after primary septoplasty","volume":"26","author":"Kahveci OK","year":"2012","journal-title":"Am J Rhinol Allergy"},{"key":"e_1_2_10_16_1","unstructured":"Position statement: nasal surgery and OSAS. 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