{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T14:07:40Z","timestamp":1790690860848,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T00:00:00Z","timestamp":1782691200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aao-hnsfjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OTO Open"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate long\u2010term swallowing outcomes in patients with HPV\u2010associated oropharyngeal squamous cell carcinoma (HPV\u2009+\u2009OPSCC) following neoadjuvant chemotherapy (NAC) and transoral robotic surgery (TORS) (NAC\u2009+\u2009S).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>Retrospective cross\u2010sectional study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Single academic institution.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients completed the MD Anderson Dysphagia Inventory (MDADI) at various time points following the completion of treatment. Patients requiring adjuvant treatment, experiencing recurrent disease, or who did not complete an MDADI at least 5 years following treatment were excluded from the study. A linear regression model was explored to determine the relationship between time since treatment and MDADI score.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 21 patients treated with the NAC\u2009+\u2009S protocol were included. The average time between treatment and the most recent follow\u2010up was 101.5 months. 1 patient had a composite MDADI score indicating poor function (&lt;60), 3 indicating adequate function (\u226560 to &lt;80), and 17 indicating optimal function (\u226580). There was no significant change in overall MDADI score (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.469), global score (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.163), emotional score (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.528), and physical score (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.903) over time. A small yet significant improvement in functional score of 1.06 points per year was seen over time (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u2009.0096).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Patients who were successfully treated with NAC\u2009+\u2009S maintain their favorable swallowing outcomes on long\u2010term follow\u2010up. A small improvement in functional MDADI sub\u2010score may represent compensatory strategies or rehabilitation over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/oto2.70267","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T15:50:14Z","timestamp":1782748214000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient\u2010Reported Swallowing Outcomes \u22655 Years After Neoadjuvant Chemotherapy and Transoral Robotic Surgery for HPV\u2010positive Oropharyngeal Carcinoma"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8805-2559","authenticated-orcid":false,"given":"Sandhya","family":"Ganesan","sequence":"first","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"},{"name":"Department of Orthopedics The Renaissance School of Medicine at Stony Brook University, Stony Brook New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-7585","authenticated-orcid":false,"given":"Sana","family":"Smaoui","sequence":"additional","affiliation":[{"name":"Department of Hearing and Speech Sciences Faculty of Allied Health Sciences, Kuwait University Jabriya Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leena","family":"Zitoun","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler P.","family":"Tufano","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Punam","family":"Thakkar","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Joshi","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology\u2013Head &amp; Neck Surgery George Washington University School of Medicine &amp; Health Sciences Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599815592157"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28250"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.8841"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.06.090"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2014.12.045"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28847"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.07.001"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26147"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24526"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26022"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pvr.2018.09.002"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/01945998211057430"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27463"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.27904"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2024.107139"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2023.3781"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2020.104853"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27631"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2023.109547"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.25778"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2020.04.021"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2018.06.014"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2018.06.013"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25923"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26887"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26950"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-021-06068-1"}],"container-title":["OTO Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oto2.70267","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/oto2.70267","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/oto2.70267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:34:15Z","timestamp":1790688855000},"score":1,"resource":{"primary":{"URL":"https:\/\/aao-hnsfjournals.onlinelibrary.wiley.com\/doi\/10.1002\/oto2.70267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,29]]},"references-count":27,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1002\/oto2.70267"],"URL":"https:\/\/doi.org\/10.1002\/oto2.70267","archive":["Portico"],"relation":{},"ISSN":["2473-974X","2473-974X"],"issn-type":[{"value":"2473-974X","type":"print"},{"value":"2473-974X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,29]]},"assertion":[{"value":"2025-07-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70267"}}