{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T20:16:37Z","timestamp":1792872997924,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:00:00Z","timestamp":1776816000000},"content-version":"vor","delay-in-days":52,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OVS"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Myopia control is crucial for pediatric eye care professionals. Although various treatments exist, their comparative efficacy, particularly in European populations, remains unclear. In real\u2010life conditions, this study aimed to compare different strategies to slow myopia progression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective, nonrandomized study evaluated the efficacy of 0.01%, 0.025%, and 0.05% atropine, defocus incorporated multiple segments\/highly aspherical lenslets (DIMS\/HAL) spectacles, combined atropine and DIMS\/HAL, and single vision spectacles in 288 European children (aged 5\u201312\u00a0years) with myopia progression (\u22650.75\u00a0D in the past 12\u00a0months). Primary outcomes were changes in spherical equivalent refraction (SER) and axial length measured every 6\u00a0months for 3\u00a0years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean cumulative 3\u2010year SER progressions were \u22120.75\u00a0\u00b1\u00a00.49, \u22120.92\u00a0\u00b1\u00a00.52, and \u22121.31\u00a0\u00b1\u00a00.75\u00a0D for the 0.05%, 0.025%, and 0.01% atropine groups, respectively, \u22121.31\u00a0\u00b1\u00a00.76\u00a0D for the DIMS\/HAL group, and \u22121.11\u00a0\u00b1\u00a00.65\u00a0D for the 0.01% atropine\u00a0+\u00a0DIMS\/HAL group, showing better myopia progression control compared to those of the control group (\u22122.14\u00a0\u00b1\u00a00.72\u00a0D). Atropine exhibited a dose\u2010dependent effect, with 0.05% atropine achieving the greatest reduction in myopia progression and axial elongation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study demonstrates the efficacy of low\u2010dose atropine and DIMS\/HAL spectacles in slowing myopia progression in European children. The 0.05% atropine exhibited the most pronounced myopia control effect.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ovs2.70007","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T03:05:34Z","timestamp":1776913534000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Control of myopia progression by low\u2010dose atropine (0.01%, 0.025% and 0.05%), defocus incorporated multiple segments\/highly aspherical lenslets spectacles, and combined therapy in European children: A 3\u2010year retrospective study"],"prefix":"10.1002","volume":"103","author":[{"given":"Manon","family":"Gr\u00e9goire","sequence":"first","affiliation":[{"name":"Department of Ophthalmology Strasbourg University Hospital  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9a","family":"Dormegny","sequence":"additional","affiliation":[{"name":"Department of 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