{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T18:49:33Z","timestamp":1790880573945,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T00:00:00Z","timestamp":1781913600000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["OVS"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the visual performance of a new daily wear presbyopia contact lens (Deseyne contact lens for presbyopia with extended depth of focus).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a randomized, crossover, and nondispensing clinical trial. Seventy\u2010eight presbyopic (45\u201370\u00a0years, mean\u00a0=\u00a053.9\u00a0years) habitual soft contact lens wearers were recruited with spherical refractive errors between \u22126.00 and +4.00\u00a0D and less than 1.25\u00a0D astigmatism. Subjects were fitted bilaterally with the Deseyne lens and a control monofocal contact lens and randomized as to which of the study lenses would be tested first. Effectiveness measures included monocular lens\u2010induced depth of focus testing\u2014the primary effectiveness measure\u2014and monocular distance, intermediate, and near visual acuity. Contrast sensitivity was also measured at mesopic luminance with and without glare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean monocular distance visual acuity was 0.00\u00a0\u00b1\u00a00.07 and \u22120.07\u00a0\u00b1\u00a00.07 logMAR with the Deseyne and control lens, respectively. The corresponding mean monocular intermediate visual acuity was +0.02\u00a0\u00b1\u00a00.11 and +0.16\u00a0\u00b1\u00a00.14 logMAR and monocular near visual acuity was +0.20\u00a0\u00b1\u00a00.11 and +0.35\u00a0\u00b1\u00a00.17 logMAR. Mean depth of focus was 2.22\u00a0\u00b1\u00a00.78\u00a0D with the Deseyne lens and 1.44\u00a0\u00b1\u00a00.67\u00a0D with the monofocal control. The mean extended depth of focus (95% CI) was thus 0.78 (0.63, 0.93)\u00a0D. Contrast sensitivity was significantly lower with the Deseyne lens at 3, 6, and 12 cycles per degree with and without glare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Deseyne contact lens for presbyopia with extended depth of focus extends the depth of focus of the eye and thus improves intermediate and near visual acuity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ovs2.70081","type":"journal-article","created":{"date-parts":[[2026,6,21]],"date-time":"2026-06-21T01:40:00Z","timestamp":1782006000000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A randomized crossover clinical trial of the Deseyne contact lens for presbyopia with extended depth of focus"],"prefix":"10.1002","volume":"103","author":[{"given":"Mark A.","family":"Bullimore","sequence":"first","affiliation":[{"name":"College of Optometry University of Houston  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles B.","family":"Slonim","sequence":"additional","affiliation":[{"name":"Iuvo BioScience, Rush, New York and Department of Ophthalmology University of South Florida Morsani College of Medicine  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Montaquila","sequence":"additional","affiliation":[{"name":"West Bay Eye Associates  Warwick Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddie","family":"Catalfamo","sequence":"additional","affiliation":[{"name":"Bruno Vision Care  Boca Raton Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giancarlo","family":"Montani","sequence":"additional","affiliation":[{"name":"CeRCA Lab University of Salento  Lecce Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,20]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444\u20100938.2010.00524.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000000780"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/opx.0000000000001017"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/icl.0000000000001013"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2021.02.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.optom.2017.04.003"},{"key":"e_1_2_9_8_1","unstructured":"Tecnis symfony extended range of vision intraocular lens.2016.https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfpma\/pma.cfm?id=P980040S065"},{"key":"e_1_2_9_9_1","volume-title":"ANSI Z80.35\u20102018 extended depth of focus intraocular lenses","year":"2019"},{"key":"e_1_2_9_10_1","unstructured":"Deseyne (vifilcon C) daily disposable soft (hydrophilic) contact lens with UV blocking for presbyopia (EDOF).2025.https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfpmn\/pmn.cfm?ID=K251683"},{"key":"e_1_2_9_11_1","unstructured":"FilippoA.WO2016108134A1. 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