{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T00:53:36Z","timestamp":1781571216932,"version":"3.54.5"},"reference-count":15,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T00:00:00Z","timestamp":1773360000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Pediatric Anesthesia"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Non\u2010intubated spontaneous ventilation anesthesia is increasingly used in adult thoracoscopic surgery, but pediatric evidence remains limited.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To compare perioperative outcomes between two anesthetic regimens in children undergoing thoracoscopic anatomical lung lesion resection: a laryngeal mask airway\u2010assisted non\u2010intubated spontaneous ventilation anesthesia and a conventional endotracheal intubation anesthesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective cohort study included children undergoing thoracoscopic anatomical lung lesion resection for pulmonary sequestration or congenital pulmonary airway malformation between April 2024 and May 2025. Children received either a conventional endotracheal intubation anesthesia or a laryngeal mask airway\u2010assisted non\u2010intubated spontaneous ventilation anesthesia. One\u2010to\u2010one propensity score matching was performed. The primary outcome was the overall incidence of postoperative pulmonary complications before discharge. Secondary outcomes were conversion to endotracheal intubation, intraoperative lowest peripheral oxygen saturation, highest end\u2010tidal carbon dioxide, postanesthesia care unit length of stay, chest tube indwelling time, and postoperative length of hospital stay. Other perioperative variables were exploratory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 198 eligible children, 50 matched pairs were analyzed. Postoperative pulmonary complications occurred in 6 of 50 children (12.0%) in the endotracheal intubation group and in 0 of 50 children (0%) in the non\u2010intubated spontaneous ventilation group (absolute risk reduction 12.0%, 95% confidence interval 3.0\u201321.0;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027). In a sensitivity analysis using Firth's logistic regression model adjusting for thoracic paravertebral block, the non\u2010intubated regimen remained associated with a lower observed incidence of postoperative pulmonary complications (adjusted odds ratio 0.06, 95% confidence interval 0.0004\u20130.76;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.029). No child in the non\u2010intubated spontaneous ventilation group required conversion to endotracheal intubation. Secondary outcomes showed modest between\u2010group differences in unadjusted analyses. However, after Holm\u2010Bonferroni adjustment, adjusted\n                      <jats:italic>p<\/jats:italic>\n                      values for secondary outcomes ranged from 0.060 to 0.208.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In this retrospective propensity\u2010score\u2010matched pediatric cohort, a laryngeal mask airway\u2010assisted non\u2010intubated spontaneous ventilation anesthesia was feasible and was not associated with worse perioperative outcomes than a conventional endotracheal intubation anesthesia. A lower observed incidence of postoperative pulmonary complications was noted. Given regimen\u2010level differences, prospective studies with standardized analgesia are needed to confirm safety and potential benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pan.70160","type":"journal-article","created":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T09:43:20Z","timestamp":1773395000000},"page":"695-702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Non\u2010Intubated Spontaneous Ventilation Versus Endotracheal Intubation Anesthesia for Pediatric Thoracoscopic Lung Resection: A Retrospective Propensity\u2010Score\u2010Matched Study"],"prefix":"10.1002","volume":"36","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3971-0053","authenticated-orcid":false,"given":"Ying","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College\/National Center for Cardiovascular Diseases  Beijing China"},{"name":"Department of Anesthesia, Capital Center for Children's Health, Capital Medical University Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1168-2882","authenticated-orcid":false,"given":"Ding","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Capital Center for Children's Health, Capital Medical University Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9485-5795","authenticated-orcid":false,"given":"Xian","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Capital Center for Children's Health, Capital Medical University Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7196-1667","authenticated-orcid":false,"given":"Yurui","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery &amp; Surgical Oncology, Capital Center for Children's Health Capital Medical University, Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6756-2804","authenticated-orcid":false,"given":"Shoudong","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Anesthesia, Capital Center for Children's Health, Capital Medical University Capital Institute of Pediatrics  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5054-0775","authenticated-orcid":false,"given":"Fuxia","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College\/National Center for Cardiovascular Diseases  Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,13]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2017.02.005"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00383-023-05445-7"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.594832"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2025.08.016"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/sja.sja_394_25"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000808"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACO.0000000000000413"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezw160"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-022-02250-z"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.14012"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd-20-3039"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2016.07.003"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31816d1268"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2025.1575412"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2024.01.043"}],"container-title":["Pediatric Anesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pan.70160","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pan.70160","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pan.70160","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T05:07:45Z","timestamp":1778994465000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pan.70160"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,13]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/pan.70160"],"URL":"https:\/\/doi.org\/10.1002\/pan.70160","archive":["Portico"],"relation":{},"ISSN":["1155-5645","1460-9592"],"issn-type":[{"value":"1155-5645","type":"print"},{"value":"1460-9592","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,13]]},"assertion":[{"value":"2025-09-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}