{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T03:25:46Z","timestamp":1791257146306,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,16]],"date-time":"2005-06-16T00:00:00Z","timestamp":1118880000000},"content-version":"vor","delay-in-days":10881,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1975,9]]},"DOI":"10.1002\/path.1711170102","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T15:34:18Z","timestamp":1119368058000},"page":"1-14","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":91,"title":["The pathology of elastase\u2010induced panacinar emphysema in hamsters"],"prefix":"10.1002","volume":"117","author":[{"given":"J. A.","family":"Hayes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Korthy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon L.","family":"Snider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,16]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.14.4.286"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.17.4.320"},{"issue":"432","key":"e_1_2_1_4_1","first-page":"1","article-title":"Studies in alphal antitrypsin deficiency","volume":"177","author":"Eriksson S.","year":"1965","journal-title":"Acta Med. Scand."},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1968.10665015"},{"key":"e_1_2_1_6_1","unstructured":"Goldring I. P. Park S. S. Greenberg L.andRatner I. M.1972Sequential anatomic changes in lungs to papain and other proteolytic enzymes.InPulmonary emphysema and proteolysis ed. by C. Mittman New York p.389."},{"key":"e_1_2_1_7_1","first-page":"481","article-title":"Enzymatically produced pulmonary emphysema. A preliminary report","volume":"6","author":"Gross P.","year":"1964","journal-title":"J. Occup. Med."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1965.10664169"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/60.5.581"},{"key":"e_1_2_1_10_1","unstructured":"Hayes J. A.1968M. D. Thesis University of Bristol.Cardiopulmonary Disease in Jamaica."},{"key":"e_1_2_1_11_1","unstructured":"Janoff A.1972Elastase\u2010like proteases of human granulocytes and alveolar macrophages.InPulmonary emphysema and proteolysis ed. by C. Mittman New York p.205."},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.128.5.1137"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106813"},{"key":"e_1_2_1_14_1","first-page":"599","article-title":"The evolution of papain emphysema in the rat","volume":"78","author":"Johanson W. G.","year":"1971","journal-title":"J. Lab. Clin. Med."},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1973.107.4.589"},{"key":"e_1_2_1_16_1","first-page":"349","article-title":"The induction of emphysema with elastase. I. The evolution of the lesion and the influence of serum","volume":"82","author":"Kaplan R.","year":"1973","journal-title":"J. Lab. Clin. Med."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.35.1.213"},{"key":"e_1_2_1_18_1","first-page":"986","article-title":"Lung volumes and mechanics in elastase\u2010induced emphysema","volume":"21","author":"Koo K. W.","year":"1973","journal-title":"Clin, Res."},{"key":"e_1_2_1_19_1","first-page":"508","article-title":"Lung volumes and mechanics following elastase and collagenase in hamsters","volume":"22","author":"Koo K. W.","year":"1974","journal-title":"Clin. Res."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.1958.7.1.69"},{"key":"e_1_2_1_21_1","first-page":"163","article-title":"Collagenases and elastases","volume":"23","author":"Mandl I.","year":"1961","journal-title":"Advan. Enzymol"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700630419"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1972.106.3.384"},{"key":"e_1_2_1_24_1","unstructured":"Orell S. R.andMazodier P.1972Pathological changes in alpha I antitrypsin deficiency.InPulmonary emphysema and proteolysis ed. by C. Mittman New York p.69."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.20.5.469"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-55-2-210"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196112212652501"},{"key":"e_1_2_1_28_1","first-page":"285","article-title":"Local arterial wall injury caused by thromboemboli","volume":"75","author":"Salyer W. R.","year":"1974","journal-title":"Amer. J. Path."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1310643"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1974.110.3.254"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.5.1.36"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101569"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.10.3.331"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/155024a0"},{"key":"e_1_2_1_35_1","doi-asserted-by":"crossref","unstructured":"Weibel E. R.1962Morphometry of the human lung.New York.","DOI":"10.1007\/978-3-642-87553-3"},{"key":"e_1_2_1_36_1","first-page":"351","article-title":"Enzymatic production of experimental emphysema in the dog. Route of exposure","volume":"109","author":"Weinbaum G.","year":"1974","journal-title":"Amer. Rev. Resp. Dis."},{"key":"e_1_2_1_37_1","first-page":"741","article-title":"Lung antiprotease: A possible primary defense against emphysema development","volume":"109","author":"Weinbaum G.","year":"1974","journal-title":"Amer. Rev. Resp. Dis."},{"key":"e_1_2_1_38_1","first-page":"576","article-title":"Suggested criteria for confirming pulmonary emphysema in the experimental animal","volume":"40","author":"Wright R. R.","year":"1968","journal-title":"Yale J. Biol. Med."}],"container-title":["The Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpath.1711170102","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/path.1711170102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T11:23:55Z","timestamp":1760959435000},"score":1,"resource":{"primary":{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/10.1002\/path.1711170102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,9]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1975,9]]}},"alternative-id":["10.1002\/path.1711170102"],"URL":"https:\/\/doi.org\/10.1002\/path.1711170102","archive":["Portico"],"relation":{},"ISSN":["0022-3417","1096-9896"],"issn-type":[{"value":"0022-3417","type":"print"},{"value":"1096-9896","type":"electronic"}],"subject":[],"published":{"date-parts":[[1975,9]]},"assertion":[{"value":"1974-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1974-10-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-06-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}