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The features of the hyperplasia were the same in the two groups. There was proliferation of sustentacular (type II) cells and compression of central cores of chief (type I) cells. It is speculated that the hyperplasia of sustentacular cells is associated in some way with the prevention of retention of sodium ions and water which characterises hypoxic cor pulmonale in \u201cblue bloaters\u201d, systemic hypertension, and ascent to high altitude with the complications of acute mountain sickness, and pulmonary and cerebral oedema.<\/jats:p>","DOI":"10.1002\/path.1711380203","type":"journal-article","created":{"date-parts":[[2005,6,21]],"date-time":"2005-06-21T14:44:13Z","timestamp":1119365053000},"page":"115-127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":63,"title":["Hyperplasia of the carotid body"],"prefix":"10.1002","volume":"138","author":[{"given":"Donald","family":"Heath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ross","family":"Jago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_1","unstructured":"Arias\u2010Stella J.:1969Human carotid body at high altitudes. 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