{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T20:09:30Z","timestamp":1761163770313,"version":"build-2065373602"},"reference-count":37,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"vor","delay-in-days":6344,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1988,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Using\n                    <jats:italic>in situ<\/jats:italic>\n                    immunohistological analysis, expression of Leu\u20108 and its correlation with other B\u2010cell markers were investigated in 21 selected lymphomas of different categories, each one expressing its own typical immunophenotype. These categories included eight follicular centroblastic\/centrocytic (CB\/CC) lymphomas, eight intermediately differentiated lymphocytic lymphomas (ILL)\/mantle zone lymphomas (MZL), and five lymphocytic lymphomas (LL) associated with chronic lymphocytic leukaemia (CLL). Four reactive lymph nodes and three tonsils were also studied using double immunolabelling procedures. Cell suspensions were also performed in three CB\/CC and four ILL\/MZL cases. Leu\u20108 was consistently expressed in ILL\/MZL and LL but it was absent in most (7\/8) CB\/CC lymphomas. In reactive tissues, the Leu\u20108\u2010positive B cells were strictly confined to the mantle zones. A close association emerged between Leu\u20101 (CD5) and Leu\u20108, both being present in ILL\/MZL and LL but absent in CB\/CC. A consistent lack of association was found between Leu\u20108 or CD5 antigens and common acute lymphoblastic leukaemia antigen (CD10) and BA\u20102 (CD9) antigen, whereas Leu\u20108 and CD5 were strictly associated with surface IgD. Reactivity with Leu\u20108 provides a means of distinguishing between CB\/CC and ILL\/MZL. Furthermore, shared immunoreactivity for Leu\u20108 in ILL\/MZL and LL may represent a potential clue to the still uncertain cellular derivation of LL\/B\u2010CLL.\n                  <\/jats:p>","DOI":"10.1002\/path.1711540205","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T13:22:36Z","timestamp":1119446556000},"page":"133-140","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Expression of Leu\u20108 surface antigen in B\u2010cell lymphomas. Correlation with other B\u2010cell markers"],"prefix":"10.1002","volume":"154","author":[{"given":"A.","family":"Carbone","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Manconi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Poletti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Gloghini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"de Paoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Volpe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V63.6.1424.1424"},{"key":"e_1_2_1_3_2","first-page":"514","article-title":"Monoclonal antibody phenotyping of B\u2010cell non\u2010Hodgkin's lymphomas. 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