{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T00:32:12Z","timestamp":1761093132416,"version":"build-2065373602"},"reference-count":7,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"vor","delay-in-days":5128,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1991,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>OPD4 is a recently described monoclonal antibody that recognizes a fixation\u2010resistant 200 kD antigen restricted to a subset of T cells. Immunolabelling with OPD4 in paraffin sections of normal lymphoid tissues and cases of malignant lymphoma was compared with that of other antibodies in common use, including the T\u2010cell restricted antibodies MTI and UCHL1 and the B\u2010cell restricted antibodies MB1, F8\u201011\u201013, and L26. OPD4 showed similar immunoreactivity to UCHL1 in normal tissues. OPD4 did not stain Reed\u2010Sternberg cells in Hodgkin's disease. In non\u2010Hodgkin's lymphomas, OPD4, like UCHL1, reacted with only 2\/22 B\u2010cell lymphomas. OPD4 was, however, less useful as a marker of T\u2010cell lymphomas, staining only 11\/32 cases, while UCHL1 stained 22\/32 cases. We conclude that OPD4 is not a useful antibody for the routine diagnosis of T\u2010cell lymphoma.<\/jats:p>","DOI":"10.1002\/path.1711640205","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T10:18:50Z","timestamp":1119435530000},"page":"119-125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Immunohistological analysis of the immunoreactivity of normal lymphoid cells and lymphomas with the monoclonal antibody OPD4"],"prefix":"10.1002","volume":"164","author":[{"given":"Jane","family":"O'Grady","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew J.","family":"Blaikie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Howie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald M.","family":"Salter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew S.","family":"Krajewski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"1339","article-title":"A novel monoclonal antibody (OPD4) recognising a helper\/inducer T cell subset","volume":"134","author":"Yoshino T","year":"1989","journal-title":"Am J Pathol"},{"key":"e_1_2_1_3_2","first-page":"1215","article-title":"Antibody L26 recognises an intracellular epitope on the B\u2010cell associated CD20 antigen","volume":"136","author":"Mason DY","year":"1990","journal-title":"Am J Pathol"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1989.tb02180.x"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1989.tb02180.x"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711540304"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1988.tb02001.x"},{"key":"e_1_2_1_8_2","first-page":"517","article-title":"The tissue distribution of Tlymphocytes expressing different CD45 polypeptides","volume":"66","author":"Janossy G","year":"1989","journal-title":"Immunology"}],"container-title":["The Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpath.1711640205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/path.1711640205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T10:41:45Z","timestamp":1761043305000},"score":1,"resource":{"primary":{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/10.1002\/path.1711640205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,6]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1991,6]]}},"alternative-id":["10.1002\/path.1711640205"],"URL":"https:\/\/doi.org\/10.1002\/path.1711640205","archive":["Portico"],"relation":{},"ISSN":["0022-3417","1096-9896"],"issn-type":[{"type":"print","value":"0022-3417"},{"type":"electronic","value":"1096-9896"}],"subject":[],"published":{"date-parts":[[1991,6]]},"assertion":[{"value":"1990-10-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1990-12-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}