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Although EM identified the likely cause of the diarrhoea in only nine cases, the majority of symptomatic HIV\u2010seropositive patients had abnormal biopsies including the presence of tubuloreticular structures, loss of microvilli, and oedema and disruption of autonomic nerves. Neuronal abnormalities were particularly common in patients with cryptosporidiosis, but no ultrastructural marker was specific to \u2018pathogen\u2010negative\u2019 diarrhoea.<\/jats:p>","DOI":"10.1002\/path.1711690113","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T12:13:33Z","timestamp":1119442413000},"page":"79-87","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Electron microscopy of rectal biopsies in HIV\u2010positive individuals"],"prefix":"10.1002","volume":"169","author":[{"given":"C.","family":"Blanshard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. S.","family":"Ellis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Tovey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. 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