{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T14:59:20Z","timestamp":1791125960331,"version":"4.1.0"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"vor","delay-in-days":4032,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1994,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Histological sections from 25 non\u2010molar pregnancies, nine partial hydatidiform moles, and 16 complete hydatidiform moles were examined (diagnosis was taken as the consensus of seven experienced histopathologists) and the fractal dimension was measured using a box\u2010counting method implemented on a microcomputer\u2010based image analysis system. The fractal dimensions of the different diagnostic categories were normally distributed with a mean of 1.50 for non\u2010molar pregnancies, 1.44 for partial moles, and 1.42 for complete moles. All the measured fractal dimensions were greater than the topological dimension (1), demonstrating that the specimens had a fractal element to their structure. There was a significant difference between the fractal dimensions of non\u2010molar pregnancies and complete moles (\n                    <jats:italic>P<\/jats:italic>\n                    =0.0005), but not between partial moles and non\u2010molar pregnancies (\n                    <jats:italic>P<\/jats:italic>\n                    =0.0823) or complete and partial moles (\n                    <jats:italic>P=<\/jats:italic>\n                    0.4400). Using the fractal dimension to predict the histopathological diagnosis assigned 56 per cent of the cases to the correct category with a kappa statistic of 0.26, so the fractal dimension, used alone, is not a useful morphometric discriminant in the diagnosis of molar and non\u2010molar pregnancy.\n                  <\/jats:p>","DOI":"10.1002\/path.1711730207","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T12:29:56Z","timestamp":1119443396000},"page":"115-118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Fractal geometric analysis of material from molar and non\u2010molar pregnancies"],"prefix":"10.1002","volume":"173","author":[{"given":"Simon S.","family":"Cross","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alec J.","family":"Howat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Stephenson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis W. K.","family":"Cotton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James C. E.","family":"Underwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.46.7.599"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0143-4004(85)80060-6"},{"key":"e_1_2_1_4_2","first-page":"248","volume-title":"Biopsy Pathology of the Endometrium","author":"Buckley CH","year":"1989"},{"key":"e_1_2_1_5_2","volume-title":"The Fractal Geometry of Nature","author":"Mandelbrot BB","year":"1982"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711660414"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711700412"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711700315"},{"key":"e_1_2_1_9_2","unstructured":"Anonymous Minitab Reference Manual Release 8. Rosemont: Minitab Statistical Software 1991;14.11\u201314.22."},{"key":"e_1_2_1_10_2","unstructured":"Anonymous.Minitab Reference Manual Release 8. Rosemont: Minitab Statistical Software 1991;9.5:9.5\u20139.10."},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.36.11.1269"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711680302"},{"key":"e_1_2_1_13_2","first-page":"38","volume-title":"Fractal Geometry: Mathematical Foundations and Applications","author":"Falconer K","year":"1990"},{"key":"e_1_2_1_14_2","first-page":"190","volume-title":"Encounters with Chaos","author":"Gulick D","year":"1992"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-4740-9"},{"key":"e_1_2_1_16_2","unstructured":"CrossSS BuryJP SilcocksPB StephensonTJ FractalCotton DWK.Geometric analysis of colorectal polyps.J Pathol(in press)."}],"container-title":["The Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpath.1711730207","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/path.1711730207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T16:55:56Z","timestamp":1761065756000},"score":1,"resource":{"primary":{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/10.1002\/path.1711730207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,6]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1994,6]]}},"alternative-id":["10.1002\/path.1711730207"],"URL":"https:\/\/doi.org\/10.1002\/path.1711730207","archive":["Portico"],"relation":{},"ISSN":["0022-3417","1096-9896"],"issn-type":[{"value":"0022-3417","type":"print"},{"value":"1096-9896","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,6]]},"assertion":[{"value":"1993-12-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1994-03-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}