{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T19:47:22Z","timestamp":1761162442301,"version":"build-2065373602"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"vor","delay-in-days":3698,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1995,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Biopsy specimens from histologically normal human gastric mucosa were examined histochemically with the use of lectins. Significant differences were found in the glycoconjugate patterns of the surface mucous cells between the body and the corresponding antrum. Two lectins (\n                    <jats:italic>Ulex europaeus<\/jats:italic>\n                    agglutinin I and\n                    <jats:italic>Ricinus communis<\/jats:italic>\n                    agglutinin I) specific for fucose and galactose residues stained the apical membrane and the intracellular (perinuclear) region of the antral mucosa more strongly than those of the body (\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0\u00b704). Body and antral biopsies from patients with\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    \u2010positive chronic active gastritis were also studied, but the lectin patterns of\n                    <jats:italic>Helicobacter pylori<\/jats:italic>\n                    \u2010infected body and antrum did not differ. On comparing these chronically infected gastric biopsies with normal antral mucosa, however, significant changes could be seen with the fucose\u2010binding lectin as well as with two other lectins (succinylated concanavalin A and peanut agglutinin).\n                  <\/jats:p>\n                  <jats:p>These differences could have been induced directly by bacterial virulence factors or could be due to non\u2010specific reactions to the inflammatory process.<\/jats:p>","DOI":"10.1002\/path.1711760112","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T13:13:50Z","timestamp":1119446030000},"page":"77-86","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Lectin\u2010binding properties of the antral and body surface mucosa in the human stomach\u2014are the differences relevant for\n                    <i>Helicobacter pylori<\/i>\n                    affinity?"],"prefix":"10.1002","volume":"176","author":[{"given":"Karl","family":"Baczako","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippa","family":"K\u00fchl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Malfertheiner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"517","volume-title":"Physiology of the Gastrointestinal Tract","author":"Ito S","year":"1981"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198601000-00006"},{"key":"e_1_2_1_4_2","first-page":"687","article-title":"Correlative scanning electron microscopy in the study of human gastric mucosa","volume":"11","author":"Bonvicini F","year":"1986","journal-title":"Scan Electron 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