{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:34:12Z","timestamp":1763746452509,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2005,6,15]],"date-time":"2005-06-15T00:00:00Z","timestamp":1118793600000},"content-version":"vor","delay-in-days":3606,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[1995,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The purpose of this study was to determine the prevalence of <jats:italic>Herpes simplex<\/jats:italic> virus (HSV) endometritis in spontaneous abortions in HIV\u2010positive women using non\u2010isotopic <jats:italic>in situ<\/jats:italic> hybridization (NISH). Post\u2010abortal endometrial curettings from 18 HIV\u2010positive women were investigated for the presence of HSV\u20101 and HSV\u20102 DNA with NISH. In addition, 18 unselected post\u2010abortal endometrial curettings in HIV\u2010negative women were used as controls, together with samples of normal proliferative and secretory endometrium. Thirteen of the 18 specimens (72 per cent) from the HIV\u2010positive study group demonstrated the presence of HSV DNA, while 2 of the 18 HIV\u2010negative group (11 per cent) showed a positive signal. Although the prevalence of HSV endometritis in the HIV\u2010positive group was significantly higher than in the HIV\u2010negative group (<jats:italic>P<\/jats:italic>&lt;0.05), a causal role for the virus in inducing the abortion remains to be determined. In addition, the significance of HSV endometritis with regard to the clinical management of HIV\u2010positive patients is as yet uncertain.<\/jats:p>","DOI":"10.1002\/path.1711760411","type":"journal-article","created":{"date-parts":[[2005,6,22]],"date-time":"2005-06-22T13:17:45Z","timestamp":1119446265000},"page":"399-402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Detection of <i>Herpes simplex<\/i> virus DNA in spontaneous abortions from HIV\u2010positive women using non\u2010isotopic <i>in situ<\/i> hybridization"],"prefix":"10.1002","volume":"176","author":[{"given":"Collen A.","family":"Wright","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zenobia","family":"Haffajee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basil","family":"Van Iddekinge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kum","family":"Cooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,6,15]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"259","article-title":"Ascending herpetic endometritis","volume":"59","author":"Schneider V","year":"1982","journal-title":"Obstet Gynecol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.44.5.400"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.42.6.592"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1994.tb00518.x"},{"key":"e_1_2_1_6_2","first-page":"127","article-title":"Arias Stella reaction with prominent nuclear pseudoinclusions simulating herpetic endometritis","volume":"4","author":"Dardi LE","year":"1982","journal-title":"Diagn Gynecol Obstet"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198307000-00004"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.54.2.167"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(86)80561-5"}],"container-title":["The Journal of Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpath.1711760411","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/path.1711760411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:34:09Z","timestamp":1761046449000},"score":1,"resource":{"primary":{"URL":"https:\/\/pathsocjournals.onlinelibrary.wiley.com\/doi\/10.1002\/path.1711760411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,8]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,8]]}},"alternative-id":["10.1002\/path.1711760411"],"URL":"https:\/\/doi.org\/10.1002\/path.1711760411","archive":["Portico"],"relation":{},"ISSN":["0022-3417","1096-9896"],"issn-type":[{"type":"print","value":"0022-3417"},{"type":"electronic","value":"1096-9896"}],"subject":[],"published":{"date-parts":[[1995,8]]},"assertion":[{"value":"1994-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"1994-12-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2005-06-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}