{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:38:23Z","timestamp":1791916703650,"version":"4.3.4"},"reference-count":169,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,12,11]],"date-time":"2014-12-11T00:00:00Z","timestamp":1418256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["pathsocjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Pathology"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Mumps is caused by the mumps virus (\n                    <jats:styled-content style=\"fixed-case\">MuV<\/jats:styled-content>\n                    ), a member of the\n                    <jats:italic>Paramyxoviridae<\/jats:italic>\n                    family of enveloped, non\u2010segmented, negative\u2010sense\n                    <jats:styled-content style=\"fixed-case\">RNA<\/jats:styled-content>\n                    viruses. Mumps is characterized by painful inflammatory symptoms, such as parotitis and orchitis. The virus is highly neurotropic, with laboratory evidence of central nervous system (\n                    <jats:styled-content style=\"fixed-case\">CNS<\/jats:styled-content>\n                    ) infection in approximately half of cases. Symptomatic\n                    <jats:styled-content style=\"fixed-case\">CNS<\/jats:styled-content>\n                    infection occurs less frequently; nonetheless, prior to the introduction of routine vaccination,\n                    <jats:styled-content style=\"fixed-case\">MuV<\/jats:styled-content>\n                    was a leading cause of aseptic meningitis and viral encephalitis in many developed countries. Despite being one of the oldest recognized diseases, with a worldwide distribution, surprisingly little attention has been given to its study. Cases of aseptic meningitis associated with some vaccine strains and a global resurgence of cases, including in highly vaccinated populations, has renewed interest in the virus, particularly in its pathogenesis and the need for development of clinically relevant models of disease. In this review we summarize the current state of knowledge on the virus, its pathogenesis and its clinical and pathological outcomes. Copyright \u00a9 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley &amp; Sons, Ltd.\n                  <\/jats:p>","DOI":"10.1002\/path.4445","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T06:31:25Z","timestamp":1410935485000},"page":"242-252","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":229,"title":["Molecular biology, pathogenesis and pathology of mumps virus"],"prefix":"10.1002","volume":"235","author":[{"given":"Steven","family":"Rubin","sequence":"first","affiliation":[{"name":"Center for Biologics Evaluation and Research Food and Drug Administration  Silver Spring MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Eckhaus","sequence":"additional","affiliation":[{"name":"Division of Veterinary Resources National Institutes of Health  Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda 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