{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:46:09Z","timestamp":1761630369254},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2005,2,7]],"date-time":"2005-02-07T00:00:00Z","timestamp":1107734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2005,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 12\u2010year\u2010old boy in third remission of an acute lymphoblastic leukaemia developed infection of lung and paranasal sinuses with <jats:italic>Aspergillus flavus<\/jats:italic> in neutropenia. Because of the high risk of leukaemia\u2010relapse bone marrow transplantation (BMT) from a matched unrelated donor was carried out despite invasive pulmonary aspergillosis (IPA). It is the first reported patient with IPA, who was successfully treated by the antifungal combination therapy with voriconazole and caspofungin therapy during myeloablative BMT. Despite 6 weeks of aplasia, a dramatic decrease of lesions highly suggestive of aspergillosis was observed after BMT. Since discharge\u2010oral voriconazole monotherapy has been continued. Pediatr Blood Cancer 2005;44:682\u2013685. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20302","type":"journal-article","created":{"date-parts":[[2005,2,8]],"date-time":"2005-02-08T03:16:59Z","timestamp":1107832619000},"page":"682-685","source":"Crossref","is-referenced-by-count":26,"title":["Successful antifungal combination therapy with voriconazole and caspofungin"],"prefix":"10.1002","volume":"44","author":[{"given":"Friedhelm","family":"Schuster","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Moelter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike B.","family":"Graubner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Kammer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernd H.","family":"Belohradsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monika","family":"F\u00fchrer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,2,7]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1086\/313445"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199908000-00010"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0507.1999.00496.x"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2002.t01-2-02002.x"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200203000-00015"},{"key":"e_1_2_5_7_2","first-page":"371","volume-title":"Programs and Abstracts of the 40th Interscience Conference on Antimicrobial Agents and Chemotherapy (Toronto)","author":"Maertens J","year":"2000"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1086\/318483"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702654"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02387554"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.9.3039-3041.2002"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.46.8.2564-2568.2002"},{"key":"e_1_2_5_13_2","first-page":"477","volume-title":"Programs and Abstracts of the 43th Interscience Conference on Antimicrobial Agents and Chemotherapy (Chicago)","author":"Gea\u2010Banacloche JC","year":"2003"},{"key":"e_1_2_5_14_2","first-page":"386","volume-title":"Programs and Abstracts of the 42th Interscience Conference on Antimicrobial Agents and Chemotherapy (San Diego)","author":"Gentina T","year":"2002"},{"key":"e_1_2_5_15_2","first-page":"443b","article-title":"Successful treatment of resistant invasive aspergillosis with combination of caspofungin acetate and voriconazole during aggressive treatment of AML including BMT","volume":"102","author":"Racil Z","year":"2003","journal-title":"Blood"},{"key":"e_1_2_5_16_2","first-page":"231b","article-title":"Efficacy of voriconazole and xaspofungin after failure of amphotericin B in a neutropenic patient with refractory acute myeloblastic leukemia (AML) and pulmonary aspergillosis","volume":"102","author":"Farhat H","year":"2003","journal-title":"Blood"},{"key":"e_1_2_5_17_2","article-title":"Rapid improvement of disseminated aspergillosis with caspofungin\/voriconazole combination in an adult leukemic patient","author":"Damaj G","year":"2003","journal-title":"Ann Hematol"},{"key":"e_1_2_5_18_2","first-page":"90","article-title":"Successful treatment of disseminated aspergillosis by caspofungin and voriconazole in a leukemic child","volume":"12","author":"Gatbois E","year":"2002","journal-title":"J Mycol Med"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/313756"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/168.3.692"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.1086\/323335"},{"key":"e_1_2_5_22_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2001.19.1.253"},{"key":"e_1_2_5_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-9114.1998.tb03152.x"},{"key":"e_1_2_5_24_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-07-2512"},{"key":"e_1_2_5_25_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3062.2002.01004.x"},{"key":"e_1_2_5_26_2","doi-asserted-by":"publisher","DOI":"10.1067\/mcp.2002.121911"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T19:43:27Z","timestamp":1696794207000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,2,7]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2005,6,15]]}},"alternative-id":["10.1002\/pbc.20302"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20302","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,2,7]]}}}