{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:49:09Z","timestamp":1771469349008,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2005,3,15]],"date-time":"2005-03-15T00:00:00Z","timestamp":1110844800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2005,3,15]],"date-time":"2005-03-15T00:00:00Z","timestamp":1110844800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Roger Maris Cancer Center, Fargo, North Dakota"},{"name":"MeritCare Children's Hospital, Fargo, North Dakota"},{"name":"MeritCare Foundation, Fargo, North Dakota"},{"name":"Children's Miracle Network, Fargo, North Dakota"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr. Blood Cancer"],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1002\/pbc.20330","type":"journal-article","created":{"date-parts":[[2005,3,16]],"date-time":"2005-03-16T04:46:38Z","timestamp":1110948398000},"page":"222-225","source":"Crossref","is-referenced-by-count":20,"title":["Successful treatment of doxorubicin and cisplatin resistant hepatoblastoma in a child with Beckwith-Wiedemann syndrome with high dose acetaminophen and <i>N<\/i>\n-acetylcysteine rescue"],"prefix":"10.1002","volume":"45","author":[{"given":"Nathan L.","family":"Kobrinsky","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diane E.","family":"Sjolander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob A.","family":"Goldenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas C.","family":"Ortmeier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,3,15]]},"reference":[{"key":"10.1002\/pbc.20330-BIB1|cit2","first-page":"847","volume-title":"Principles and practice of pediatric oncology","author":"Tomlinson","year":"2002"},{"key":"10.1002\/pbc.20330-BIB2|cit3","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1021\/tx00034a019","article-title":"Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver microsomes and their kinetics","volume":"6","author":"Patten","year":"1993","journal-title":"Chem Res Toxicol"},{"key":"10.1002\/pbc.20330-BIB3|cit4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0140-6736(71)91125-1","article-title":"Plasma-paracetamol half-life and hepatic necrosis in patients with paracetamol overdosage","volume":"1","author":"Prescott","year":"1971","journal-title":"Lancet"},{"key":"10.1002\/pbc.20330-BIB4|cit5","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0140-6736(73)90466-2","article-title":"Hepatic damage and death from overdose of paracetamol","volume":"1","author":"Clark","year":"1973","journal-title":"Lancet"},{"key":"10.1002\/pbc.20330-BIB5|cit6","first-page":"54","article-title":"Role of glutathione in prevention of acetaminophen-induced hepatotoxicity by N-acetyl-l-cysteine in vivo. Studies with N-acetyl-l-cysteine in mice","volume":"238","author":"Corcoran","year":"1986","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1002\/pbc.20330-BIB6|cit7","first-page":"536","article-title":"Evidence that acetaminophen and N-hydroxyacetaminophen form a common arylating intermediate N-acetyl-p-benzoquinoneimine","volume":"18","author":"Corcoran","year":"1980","journal-title":"Mol Pharmacol"},{"key":"10.1002\/pbc.20330-BIB7|cit8","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0140-6736(74)92649-X","article-title":"Successful treatment of severe paracetamol overdosage with cysteamine","volume":"1","author":"Prescott","year":"1974","journal-title":"Lancet"},{"key":"10.1002\/pbc.20330-BIB8|cit9","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0140-6736(77)90612-2","article-title":"Treatment of paracetamol (acetaminophen) poisoning with N-acetyl-cysteine","volume":"2","author":"Prescott","year":"1977","journal-title":"Lancet"},{"key":"10.1002\/pbc.20330-BIB9|cit10","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1136\/bmj.2.6198.1097","article-title":"Intravenous N-acetylcystine: The treatment of choice for paracetamol poisoning","volume":"2","author":"Prescott","year":"1979","journal-title":"Br Med J"},{"key":"10.1002\/pbc.20330-BIB10|cit11","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1749-6632.1988.tb30145.x","article-title":"Hepatic metabolism and carcinogenesis: Its role in hepatoma and adenocarcinoma formation","volume":"534","author":"Feuer","year":"1988","journal-title":"Ann NY Acad Sci"},{"key":"10.1002\/pbc.20330-BIB11|cit12","first-page":"4866","article-title":"Implications for therapy of drug-metabolizing enzymes in human colon cancer","volume":"49","author":"Mekhail-Ishak","year":"1989","journal-title":"Cancer Res"},{"key":"10.1002\/pbc.20330-BIB12|cit13","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1002\/hep.1840050502","article-title":"Acetaminophen hepatotoxicity and targeted rescue: A model for specific chemotherapy of hepatocellular carcinoma","volume":"5","author":"Wu","year":"1985","journal-title":"Hepatology"},{"key":"10.1002\/pbc.20330-BIB13|cit14","doi-asserted-by":"crossref","first-page":"202","DOI":"10.3109\/07357909609012140","article-title":"Treatment of advanced malignancies with high-dose acetaminophen and N-acetylcysteine rescue","volume":"14","author":"Kobrinsky","year":"1996","journal-title":"Cancer Invest"},{"key":"10.1002\/pbc.20330-BIB14|cit15","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/00008390-200304000-00013","article-title":"Phase I trial of high dose paracetamol and carmustine in patients with metastatic melanoma","volume":"13","author":"Wolchok","year":"2003","journal-title":"Melanoma Res"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20330","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20330","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1002\/pbc.20330\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T11:42:38Z","timestamp":1625398958000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20330"}},"subtitle":["High Dose Acetaminophen for Hepatoblastoma"],"short-title":[],"issued":{"date-parts":[[2005,3,15]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,8]]}},"URL":"https:\/\/doi.org\/10.1002\/pbc.20330","archive":["Portico"],"relation":{},"ISSN":["1545-5009"],"issn-type":[{"value":"1545-5009","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3,15]]}}}