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She was treated with partial cystectomy. After a 12\u2010year disease\u2010free interval, she was diagnosed with a second leiomyosarcoma of the bladder. This case supports the relationship between the genetic form of retinoblastoma and leiomyosarcoma and illustrates the necessity for extensive follow\u2010up and well\u2010defined treatment of secondary neoplasms. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20506","type":"journal-article","created":{"date-parts":[[2006,2,9]],"date-time":"2006-02-09T20:52:20Z","timestamp":1139518340000},"page":"811-814","source":"Crossref","is-referenced-by-count":14,"title":["A second leiomyosarcoma in the urinary bladder of a child with a history of retinoblastoma 12 years following partial cystectomy"],"prefix":"10.1002","volume":"46","author":[{"given":"Benjamin","family":"Brucker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Ernst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Meadows","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Zderic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,2,7]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1200\/JCO.1995.13.2.532","article-title":"Leiomyosarcoma of the urinary bladder after cyclophosphamide","volume":"13","author":"Perdersen\u2010Bergaard J","year":"1995","journal-title":"J Clin Oncol"},{"key":"e_1_2_4_3_2","first-page":"104","article-title":"Retinoblastoma","volume":"11","author":"Lueder GT","year":"1994","journal-title":"Semin Diagn Path"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550150066037"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.56.3.233"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000282511"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1080\/003655901750292060"},{"key":"e_1_2_4_8_2","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.5858\/2001-125-1231-AHGPLO","article-title":"A high\u2010grade primary leiomyosarcoma of the bladder in survivor of retinoblastoma","volume":"125","author":"Liang S","year":"2001","journal-title":"Arch Pathol Lab Med"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(02)01701-6"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.MP.0000068237.38715.D9"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000071109"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(196810)22:4<833::AID-CNCR2820220422>3.0.CO;2-I"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199801)30:1<59::AID-MPO14>3.0.CO;2-3"},{"key":"e_1_2_4_14_2","first-page":"414","article-title":"The significance of p16, cyclin D1 and pRb expression in soft tissue leiomyosarcoma","volume":"28","author":"Xu J","year":"1999","journal-title":"(Zhonghua Bing Li Xue Za Zhi)"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.10451"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)56306-5"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,14]],"date-time":"2023-10-14T15:03:31Z","timestamp":1697295811000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,7]]},"references-count":15,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1002\/pbc.20506"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20506","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,7]]}}}