{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,6]],"date-time":"2024-09-06T13:41:49Z","timestamp":1725630109488},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2005,8,2]],"date-time":"2005-08-02T00:00:00Z","timestamp":1122940800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hemoglobin Hammersmith, a rare, unstable hemoglobin variant, was diagnosed in a 9\u2010year\u2010old Japanese girl. She presented with the typical manifestations of this disorder, including neonatal hyperbilirubinemia, followed by progressive hepatosplenomegaly, jaundice, and bilirubinuria. Because of severe hemolytic anemia, she received transfusions of red blood cells every 3 to 4 weeks. However, she underwent splenectomy at the age of 4 years and has continued to be in partial remission without requiring further transfusions. DNA sequence analysis of the polymerase chain reaction\u2010amplified \u03b2\u2010globin gene revealed a point mutation (T\u2009\u2192\u2009C) in the second nucleotide of the 42nd codon of the \u03b2\u2010globin chain (\u03b2 42(CD1) Phe\u2009\u2192\u2009Ser). Pediatric Blood Cancer 2006;47:839\u2013841. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20533","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T22:22:37Z","timestamp":1123107757000},"page":"839-841","source":"Crossref","is-referenced-by-count":9,"title":["Hemoglobin Hammersmith [\u03b2 42(CD1) Phe\u2009\u2192\u2009Ser] causing severe hemolytic anemia in a Japanese girl"],"prefix":"10.1002","volume":"47","author":[{"given":"Masaharu","family":"Akiyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shizuko","family":"Murayama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Yokoi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaki","family":"Yanagisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukio","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Yamashiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshikatsu","family":"Eto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohji","family":"Fujisawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2005,8,2]]},"reference":[{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/216663a0"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.45.527.629"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(73)80383-9"},{"key":"e_1_2_2_5_2","first-page":"53","article-title":"Hemoglobin Chiba: Hb Hammersmith in a Japanese girl","volume":"38","author":"Ohba Y","year":"1975","journal-title":"Nippon Ketsueki Gakkai Zasshi"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.3109\/03630268108996914"},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00484942"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-198608010-00004"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb08026.x"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/03630269209005672"},{"key":"e_1_2_2_11_2","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1097\/00043426-199811000-00011","article-title":"Hb Hammersmith [\u03b2 42 (CD1) Phe\u2009\u2192\u2009Ser]: Occurrence as a de novo mutation in black monozygotic twins with multiple congenital anomalies","volume":"20","author":"Tuohy AM","year":"1998","journal-title":"J Pediatr Hematol Oncol"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20533","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20533","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T10:59:59Z","timestamp":1696676399000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20533"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,2]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,11]]}},"alternative-id":["10.1002\/pbc.20533"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20533","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8,2]]}}}