{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:58:41Z","timestamp":1790258321604,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2005,11,10]],"date-time":"2005-11-10T00:00:00Z","timestamp":1131580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2007,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A major hallmark of NF1 is the development of benign tumors, including peripheral neurofibromas, plexiform neurofibromas, gliomas of the optic tract, other low grade gliomas, and pheochromocytomas. Hepatoblastoma have not been previously reported in patients with neurofibromatosis type 1. We present a case of a 9\u2010month\u2010old boy diagnosed with both hepatoblastoma and neurofibromatosis type 1. Hepatoblastoma occurs in association with several well\u2010described cancer predisposition syndromes, including familial adenomatous polyposis, Beckwith\u2013Wiedemann syndrome, Li\u2010Fraumeni syndrome, trisomy 18, and glycogen storage disease type I. This paper describes a case of hepatoblastoma diagnosed in association with neurofibromatosis type 1. Pediatr Blood Cancer 2007;49:357\u2013359. \u00a9 2005 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20663","type":"journal-article","created":{"date-parts":[[2005,11,16]],"date-time":"2005-11-16T21:52:19Z","timestamp":1132177939000},"page":"357-359","source":"Crossref","is-referenced-by-count":24,"title":["Hepatoblastoma in a child with neurofibromatosis type I"],"prefix":"10.1002","volume":"49","author":[{"given":"Canan","family":"U\u00e7ar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00dcmran","family":"\u00c7al\u0131\u015fkan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hatice","family":"Toy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Engin","family":"G\u00fcnel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2005,11,10]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.2870130206"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1997.03550010065042"},{"key":"e_1_2_4_4_2","first-page":"21","volume-title":"Principles and practice of pediatric oncology","author":"Plon SE","year":"2002"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19931101)72:9<2746::AID-CNCR2820720936>3.0.CO;2-W"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(78)80362-X"},{"key":"e_1_2_4_7_2","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1182\/blood.V79.5.1311.1311","article-title":"Monosomy 7 myeloproliferative disease in children with neurofibromatosis, type 1: Epidemiology and molecular analysis","volume":"79","author":"Shannon KM","year":"1992","journal-title":"Blood"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199403033300912"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199711000-00015"},{"key":"e_1_2_4_10_2","first-page":"2015","volume-title":"Nelson Textbook of Pediatrics","author":"Haslam RHA","year":"2004"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.10167"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9896(199804)184:4<360::AID-PATH1263>3.0.CO;2-H"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0748-7983(05)80083-6"},{"key":"e_1_2_4_14_2","volume-title":"Cancer incidence and survival among children and adolescents: United States SEER program 1975\u20131995","author":"Bulterys M","year":"1999"},{"key":"e_1_2_4_15_2","first-page":"847","volume-title":"Principles and practice of pediatric oncology","author":"Tomlinson GE","year":"2002"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3468(75)90095-0"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198212000-00001"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(83)80005-7"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711170304"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(87)90866-3"},{"key":"e_1_2_4_21_2","first-page":"3032","article-title":"Increased risk of hepatoblastoma among immature children with a lower birth weight","volume":"58","author":"Tanimura M","year":"1998","journal-title":"Cancer Res"},{"key":"e_1_2_4_22_2","doi-asserted-by":"crossref","first-page":"2849","DOI":"10.1182\/blood.V90.7.2849","article-title":"Thrombopoietin in patients with hepatoblastoma","volume":"90","author":"Komura\u2010Naito E","year":"1997","journal-title":"Blood"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20663","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20663","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T01:03:04Z","timestamp":1697677384000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20663"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,10]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,9]]}},"alternative-id":["10.1002\/pbc.20663"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20663","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,10]]}}}