{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:30:58Z","timestamp":1762003858687},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2006,2,7]],"date-time":"2006-02-07T00:00:00Z","timestamp":1139270400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2007,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Fournier's gangrene (FG) is a fulminant necrotizing fasciitis of the external genitalia. Few reports of FG exist in patients with hematologic malignancies. We describe a case of fatal FG in a 21\u2010year\u2010old man with acute lymphoblastic leukemia who was receiving remission\u2010induction chemotherapy. Despite early local surgery, administration of appropriate antibiotics, resurgery for wider debridement and aggressive ICU support he succumbed while pancytopenic to septic shock, 26 days after initiation of chemotherapy. Multi\u2010drug resistant <jats:italic>Pseudomonas aeruginosa<\/jats:italic> was isolated from blood and scrotal cultures obtained at initial surgery. FG is a fulminant infection, especially in the face of profound cytopenias. Pediatr Blood Cancer 2007;49:862\u2013864. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20695","type":"journal-article","created":{"date-parts":[[2006,1,19]],"date-time":"2006-01-19T21:57:13Z","timestamp":1137707833000},"page":"862-864","source":"Crossref","is-referenced-by-count":9,"title":["Fatal Fournier's gangrene in a young adult with acute lymphoblastic leukemia"],"prefix":"10.1002","volume":"49","author":[{"given":"Elpis","family":"Mantadakis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charalampos","family":"Pontikoglou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen A.","family":"Papadaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Aggelidakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Samonis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1,19]]},"reference":[{"key":"e_1_2_4_2_2","first-page":"345","article-title":"Gangrene foudroyante de la verge","volume":"3","author":"Fournier JA","year":"1883","journal-title":"Semaine Medicale"},{"key":"e_1_2_4_3_2","first-page":"149","article-title":"Fournier's gangrene: Historic (1764\u20101978) versus contemporary (1979\u20131988) differences in etiology and clinical importance","volume":"59","author":"Stephens BJ","year":"1993","journal-title":"Am Surg"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2000.01497.x"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.10110"},{"key":"e_1_2_4_6_2","first-page":"655","article-title":"Necrotizing anorectal and perineal infections","volume":"86","author":"Bubrick MP","year":"1979","journal-title":"Surgery"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19871001)60:7<1462::AID-CNCR2820600710>3.0.CO;2-A"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860615)57:12<2291::AID-CNCR2820571210>3.0.CO;2-4"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002770050370"},{"key":"e_1_2_4_10_2","first-page":"235","article-title":"Fournier's gangrene or fulminant necrotizing fasciitis of the scrotum and penis as a complication of granulocytopenia in a patient with acute myelogenous leukaemia (AML)","volume":"32","author":"Heurkens AH","year":"1988","journal-title":"Neth J Med"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1159\/000249770"},{"key":"e_1_2_4_12_2","first-page":"180","article-title":"Fournier's gangrene","volume":"28","author":"Joo P","year":"1985","journal-title":"Can J Surg"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V85.8.2025.bloodjournal8582025"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(90)80088-5"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-200109000-00031"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(98)00025-3"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-002-0525-9"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701438"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1086\/514909"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20695","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20695","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,14]],"date-time":"2023-11-14T20:50:32Z","timestamp":1699995032000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20695"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,1,19]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,11]]}},"alternative-id":["10.1002\/pbc.20695"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20695","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,1,19]]}}}