{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T12:00:14Z","timestamp":1780056014508,"version":"3.54.0"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2006,1,24]],"date-time":"2006-01-24T00:00:00Z","timestamp":1138060800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Hematologic abnormalities following solid organ transplantation are infrequently autoimmune in origin. We present a series of autoimmune cytopenias developing as a late complication of pediatric cardiac transplantation. Autoimmune cytopenias represented include autoimmune hemolytic anemia, acquired Glanzmann thrombasthenia, and idiopathic thrombocytopenic purpura. Standard therapies were used in each patient without sustainable results. Eventually, each patient was treated with and responded to rituximab. In this report, we review these cases, propose potential mechanisms for development of autoimmune cytopenias, and discuss our experience with rituximab in managing refractory autoimmune cytopenias. Pediatr Blood Cancer 2007;48:339\u2013344. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20761","type":"journal-article","created":{"date-parts":[[2006,1,24]],"date-time":"2006-01-24T22:51:14Z","timestamp":1138143074000},"page":"339-344","source":"Crossref","is-referenced-by-count":25,"title":["Acquired immune cytopenias post\u2010cardiac transplantation respond to rituximab"],"prefix":"10.1002","volume":"48","author":[{"given":"Ven\u00e9e N.","family":"Tubman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie","family":"Smoot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew M.","family":"Heeney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,1,3]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-199203000-00002"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2003.12.040"},{"key":"e_1_2_5_4_2","first-page":"817","article-title":"Guillain\u2010barre syndrome after heart transplantation","volume":"11","author":"Baldwin RT","year":"1992","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_5_5_2","first-page":"785","article-title":"Refractory immune thrombocytopenia after heart transplantation: A case report","volume":"14","author":"Dhar SC","year":"1995","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(00)00104-2"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900177"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2004.00256.x"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701017"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1993.tb17137.x"},{"key":"e_1_2_5_11_2","first-page":"445","article-title":"Autoimmune pancytopenia following allogeneic bone marrow transplantation","volume":"6","author":"Klumpp TR","year":"1990","journal-title":"Bone Marrow Transplant"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05173.x"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008389119525"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.8.2825"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2004.04.006"},{"key":"e_1_2_5_16_2","first-page":"1006","article-title":"Rituximab for refractory childhood autoimmune hemolytic anemia","volume":"4","author":"Motto DG","year":"2002","journal-title":"Isr Med Assoc J"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2002.02686.x"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-003-0740-z"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.20761","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.20761","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T00:52:29Z","timestamp":1696726349000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.20761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1,3]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2007,3]]}},"alternative-id":["10.1002\/pbc.20761"],"URL":"https:\/\/doi.org\/10.1002\/pbc.20761","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,1,3]]}}}