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The clinical presentation of ceftriaxone\u2010induced HA is usually abrupt with sudden onset of pallor, tachypnea, cardio\u2010respiratory arrest and shock. Acute renal failure (ARF) has been reported in 41% of such cases with a high fatality rate. We report a pediatric patient with ARF complicating ceftriaxone\u2010induced HA who survived. Ceftriaxone is a commonly used drug, and early recognition of HA and institution of supportive care, including dialysis is likely to improve the outcome. Pediatr Blood Cancer 2008;50:139\u2013142. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.20839","type":"journal-article","created":{"date-parts":[[2006,4,6]],"date-time":"2006-04-06T21:54:12Z","timestamp":1144360452000},"page":"139-142","source":"Crossref","is-referenced-by-count":29,"title":["Ceftriaxone induced hemolysis complicated by acute renal failure"],"prefix":"10.1002","volume":"50","author":[{"given":"Gaurav","family":"Kapur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudolph P.","family":"Valentini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tej K.","family":"Mattoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Indira","family":"Warrier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abubakr A.","family":"Imam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,19]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1592\/phco.22.8.630.33203"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1987.27688071694.x"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1999.39111239.x"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001340000598"},{"key":"e_1_2_4_6_2","first-page":"368","article-title":"Ceftriaxone associated hemolysis","volume":"111","author":"Maraspin V","year":"1999","journal-title":"Wien Klin Wochenschr"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199512000-00023"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70418-3"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(95)70417-5"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(96)70456-0"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70236-7"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01434.x"},{"key":"e_1_2_4_13_2","first-page":"1390","article-title":"Severe hemolysis induced by ceftriaxone in a child with sickle cell anemia","volume":"26","author":"Viner Y","year":"2000","journal-title":"Pediatr Infect Dis J"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1754.2002.00778.x"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.5858\/2004-128-905-ACOAHA"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PCC.0000161285.12396.FF"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.1991.31291142951.x"},{"key":"e_1_2_4_18_2","first-page":"25S","article-title":"Ceftriaxone induced hemolytic anemia","volume":"33","author":"Lo G","year":"1993","journal-title":"Transfusion"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1998.239_a.x"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-0691.1999.tb00441.x"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1537-2995.2000.40121543.x"},{"key":"e_1_2_4_22_2","first-page":"115","article-title":"Drug\u2010induced hemolytic anemias: Increasing complications to therapeutic interventions","volume":"12","author":"Wright MS","year":"1999","journal-title":"Clin Lab Sci"},{"key":"e_1_2_4_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-7963(90)70249-0"},{"key":"e_1_2_4_24_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1985.tb04069.x"},{"key":"e_1_2_4_25_2","first-page":"F446","article-title":"Pathogenic mechanisms in experimental hemoglobinuric acute renal failure","volume":"256","author":"Zagar RA","year":"1989","journal-title":"Am J Physiol"}],"container-title":["Pediatric Blood &amp; 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