{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T16:21:24Z","timestamp":1787242884355,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2007,11,16]],"date-time":"2007-11-16T00:00:00Z","timestamp":1195171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2008,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peripheral T\u2010cell lymphomas (PTCL) are very rare in children and this has prevented assessment of best treatment and prognosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Procedure<\/jats:title>\n                    <jats:p>Registry\u2010based experience in England, Scotland and Wales over a 20\u2010year period was studied to address these shortfalls. Anaplastic large cell lymphoma and mycosis fungoides were excluded due to recent publications describing UK experience with these disorders.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty\u2010five cases were identified, comprising 1.6% of non\u2010Hodgkin lymphoma (NHL) registrations; 17 (68%) children with PTCL\u2010unspecified (PTCL\u2010u), 3 (12%) with angiocentric PTCL, 3 (12%) with angioimmunoblastic PTCL, and 2 (8%) with subcutaneous panniculitis\u2010like T\u2010cell lymphoma. Eighteen children were male, with a male\/female ratio of 2.6:1. Median age was 7 (range 1\u201314) years. Eleven children (44%) died and actuarial survival was 76% at 1 year, 64% at 3 years and 59% at 5 years. Treatments given were subdivided between group T (regimens for T NHL or acute lymphoblastic leukaemia) or group B (regimens for B NHL). Amongst the 17 children with PTCL\u2010u, 9\/12 children in group T survived compared with 1\/5 group B.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Children's Cancer and Leukaemia Group recommendation that children with PTCL\u2010u receive group T therapy is supported by this series. The numbers of children with other types of PTCL were too small to allow conclusions on best therapy. Pediatr Blood Cancer 2008;50:784\u2013787. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pbc.21293","type":"journal-article","created":{"date-parts":[[2007,11,16]],"date-time":"2007-11-16T18:16:20Z","timestamp":1195236980000},"page":"784-787","source":"Crossref","is-referenced-by-count":62,"title":["Peripheral T\u2010cell lymphoma in childhood: Population\u2010based experience in the United Kingdom over 20 years"],"prefix":"10.1002","volume":"50","author":[{"given":"Rachael","family":"Windsor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Stiller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,11,16]]},"reference":[{"key":"e_1_2_12_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.5.1361.1361"},{"key":"e_1_2_12_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdf033"},{"key":"e_1_2_12_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.12.4514"},{"key":"e_1_2_12_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-06-2508"},{"key":"e_1_2_12_6_2","first-page":"332","article-title":"Classification, staging and end\u2010results of treatment of childhood non\u2010Hodgkin's lymphoma. Dissimilarities from lymphoma in adults","volume":"7","author":"Murphy SB","year":"1980","journal-title":"Semin Oncol"},{"key":"e_1_2_12_7_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.2.359"},{"key":"e_1_2_12_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(95)00428-9"},{"key":"e_1_2_12_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2002.03482.x"},{"key":"e_1_2_12_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11780"},{"key":"e_1_2_12_11_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1989.7.2.186"},{"key":"e_1_2_12_12_2","first-page":"29","article-title":"Treatment of patients with aggressive lymphomas: An overview","volume":"10","author":"Urba WJ","year":"1990","journal-title":"J Natl Cancer Inst Monogr"},{"key":"e_1_2_12_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1989.123"},{"key":"e_1_2_12_14_2","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.1999.1083"},{"key":"e_1_2_12_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1992.tb06423.x"},{"key":"e_1_2_12_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(95)90164-7"},{"key":"e_1_2_12_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401704"},{"key":"e_1_2_12_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401784"},{"key":"e_1_2_12_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.2001.tb00804.x"},{"key":"e_1_2_12_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.1989.tb02144.x"},{"key":"e_1_2_12_21_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1996.tb16249.x"},{"key":"e_1_2_12_22_2","unstructured":"ParkinDM Kram\u00e1rov\u00e1E DraperGJ et al.International Incidence of Childhood Cancer Volume 2. IARC Scientific Publications No 144. Lyon: International Agency for Research on Cancer 1998."},{"key":"e_1_2_12_23_2","doi-asserted-by":"publisher","DOI":"10.1080\/1042819021000030054"},{"key":"e_1_2_12_24_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdh392"},{"key":"e_1_2_12_25_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008418727472"},{"key":"e_1_2_12_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950230106"},{"key":"e_1_2_12_27_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.6.1368"},{"key":"e_1_2_12_28_2","first-page":"1109","article-title":"Non\u2010ALC peripheral T\u2010cell lymphomas in children: Report on two cases and review of the literature","volume":"85","author":"Massimino M","year":"2000","journal-title":"Haematologica"},{"key":"e_1_2_12_29_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-03-1306"},{"key":"e_1_2_12_30_2","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.1252"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.21293","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.21293","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T23:46:41Z","timestamp":1697068001000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.21293"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,11,16]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,4]]}},"alternative-id":["10.1002\/pbc.21293"],"URL":"https:\/\/doi.org\/10.1002\/pbc.21293","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,11,16]]}}}