{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T12:55:14Z","timestamp":1769604914067,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2008,2,7]],"date-time":"2008-02-07T00:00:00Z","timestamp":1202342400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2008,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Radiotherapy is associated with an increased survival rate in children with brain tumors, but also with cognitive decline. This study examined the time\u2010dependent effects of radiation treatment on adaptive functioning in children with brain tumors. The potentially mediating effects of attention span (Trial 1 of the Rey Auditory Verbal Learning Test [RAVLT]) assessed within 7 years of diagnosis were explored.<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>Twenty\u2010two children treated with cranial radiation for third ventricle or cerebellar tumors were included in this archival study. The mean age at diagnosis was 7.62 years (SD\u2009=\u20094.78) and 10.16 years (SD\u2009=\u20093.83) at evaluation. We examined the extent to which auditory attention span was able to mediate the relationship between time elapsed since the initiation of radiation treatment (M\u2009=\u20092.43 years; SD\u2009=\u20092.37) and adaptive functioning (Vineland Adaptive Behavior Scales [VABS]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Attention span was found to mediate the relationship between time since the initiation of radiation and daily living skills. These findings were shown to be specific to attention and not a reflection of generalized neuropsychological decline, nor were they a result of increasing time since diagnosis in and of itself.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this study suggest that time since radiation may directly decrease attention and poor attention in turn may be associated with lower adaptive functioning on tasks of daily living. Pediatr Blood Cancer 2008;50:1253\u20131257. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.21495","type":"journal-article","created":{"date-parts":[[2008,2,7]],"date-time":"2008-02-07T18:46:50Z","timestamp":1202410010000},"page":"1253-1257","source":"Crossref","is-referenced-by-count":17,"title":["Attention mediates radiation's impact on daily living skills in children treated for brain tumors"],"prefix":"10.1002","volume":"50","author":[{"given":"Aimilia","family":"Papazoglou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tricia Z.","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robin D.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary K.","family":"Morris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas S.","family":"Krawiecki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,2,7]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"CBTRUS.Statistical Report: Primary Brain Tumors in the United States 1998\u20132002. Published by the Central Brain Tumor Registry of the United States.2005."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/jpepsy\/jsm018"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200306000-00008"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-006-9187-0"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.06.117"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/pon.855"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1159\/000120325"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20251"},{"key":"e_1_2_6_10_2","first-page":"27","article-title":"The contribution of the cerebellum to mental and social functions in developmental age","volume":"26","author":"Riva D","year":"2000","journal-title":"Fiziol Cheloveka"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21062"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0147-0272(03)00026-6"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/01688639408402615"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00301666"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1215\/S1152851704000079"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(1998)30:1 <75::AID-MPO11>3.0.CO;2-U"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1994.12.12.2621"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.11.3476"},{"key":"e_1_2_6_19_2","first-page":"1016","volume-title":"Neuropsychological Assessment","author":"Lezak MD","year":"2004"},{"key":"e_1_2_6_20_2","first-page":"2004","volume-title":"The Stanford\u2010Binet intelligence scale: Technical manual","author":"Thorndike R","year":"1986"},{"key":"e_1_2_6_21_2","first-page":"301","volume-title":"Interview edition survey form manual: Vineland Adaptive Behavior Scales","author":"Sparrow SS","year":"1994"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1037\/0090-5550.50.4.375"},{"key":"e_1_2_6_23_2","first-page":"523","article-title":"Test retest comparability and control subject data for the Rey\u2010Auditory Verbal Learning Test and Rey\u2010Osterrieth\/Taylor Complex Figures","volume":"7","author":"Delaney RC","year":"1992","journal-title":"Arch Clin Neuropsychol"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1080\/13854049008401506"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.1080\/13854049108404102"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1080\/13854049008401496"},{"key":"e_1_2_6_27_2","first-page":"545","volume-title":"Applied Multiple Regression\/Correlation Analysis for the Behavioral Sciences","author":"Cohen J","year":"1983"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1037\/0022-0167.53.3.372"},{"key":"e_1_2_6_29_2","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1017\/S1355617701020112","article-title":"Attentional processes and their remediation in children treated for cancer: A literature review and the development of a therapeutic approach","volume":"8","author":"Butler R","year":"2002","journal-title":"J Int Neuropsychol Soc"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2004.04.128"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.21495","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.21495","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T11:37:29Z","timestamp":1697629049000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.21495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,2,7]]},"references-count":29,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2008,6]]}},"alternative-id":["10.1002\/pbc.21495"],"URL":"https:\/\/doi.org\/10.1002\/pbc.21495","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,2,7]]}}}