{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:51:29Z","timestamp":1760982689075},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T00:00:00Z","timestamp":1215734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2008,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We present a case of pancytopenia in a 9\u2010month\u2010old infant with total parenteral nutrition (TPN) dependence due to short bowel syndrome. Bone marrow examination revealed left\u2010shifted myeloid maturation, erythroid and myeloid dysplasia with normal iron stores. Serum copper level was 2 \u00b5m\/dl (normal range 90\u2013190 mcg\/dl). After supplementation, copper levels normalized at 143 mcg\/dl, and the macrocytic anemia, neutropenia, and thrombocytopenia resolved. Copper deficiency should be considered in the differential diagnosis of cytopenias and myelodsyplasia, particularly in the growing number of pediatric patients with TPN dependency or malabsorption. Pediatr Blood Cancer 2008;51:693\u2013695. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.21661","type":"journal-article","created":{"date-parts":[[2008,7,11]],"date-time":"2008-07-11T20:42:27Z","timestamp":1215808947000},"page":"693-695","source":"Crossref","is-referenced-by-count":13,"title":["Pancytopenia with myelodysplasia due to copper deficiency"],"prefix":"10.1002","volume":"51","author":[{"given":"Lauren B.","family":"Angotti","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ginell R.","family":"Post","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy S.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jocelyn A.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle P.","family":"Hudspeth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Lazarchick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2008,7,11]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2007.02.009"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0115426504019003305"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.20864"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02898451"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/67.5.1012S"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(72)80449-9"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.12121"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.21661","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.21661","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T19:57:22Z","timestamp":1697659042000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.21661"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,11]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,11]]}},"alternative-id":["10.1002\/pbc.21661"],"URL":"https:\/\/doi.org\/10.1002\/pbc.21661","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,11]]}}}