{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T10:19:56Z","timestamp":1778494796263,"version":"3.51.4"},"reference-count":17,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2008,12,4]],"date-time":"2008-12-04T00:00:00Z","timestamp":1228348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2009,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A child was referred for evaluation after prenatal diagnosis with macrosomia, clitoromegaly, labial hypertrophy, and a left ovarian cyst. The karyotype was 46,XX. The postnatal pelvic ultrasound was normal. High levels of anti\u2010mullerian hormone and testosterone led to a hCG stimulation test, which was followed by isosexual precocious puberty and the appearance of a bilateral ovarian enlargement with a left tumoral mass. A left ovarian tumorectomy revealed a fibrothecoma. Six weeks later, a tumoral relapse occurred and completion of oophorectomy revealed a juvenile granulosa cell tumor (JGCT). Whereas hormonal levels decreased after surgery, a new rise associated with an enlargement of the right ovary led to the diagnosis of right JGCT. A right oophorectomy was proposed to the parents, who declined further surgery. After 2 months, the hormonal levels normalized. This case illustrates the confusing overlap between developmental and neoplastic biology in neonates. Pediatr Blood Cancer 2009;52:401\u2013403. \u00a9 2008 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.21775","type":"journal-article","created":{"date-parts":[[2008,12,4]],"date-time":"2008-12-04T15:54:17Z","timestamp":1228406057000},"page":"401-403","source":"Crossref","is-referenced-by-count":13,"title":["Neonatal bilateral ovarian sex cord stromal tumors"],"prefix":"10.1002","volume":"52","author":[{"given":"Carmen","family":"Capito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle","family":"Flechtner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabeth","family":"Thibaud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophie","family":"Emond","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicolas","family":"Kalfa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francis","family":"Jaubert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Sarnacki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,1,8]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2001.22939"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2005.01.005"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20233"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800311"},{"key":"e_1_2_5_6_2","first-page":"439","article-title":"Ovarian sex cord\u2010stromal tumors in children and adolescents","volume":"50","author":"Schneider DT","year":"2005","journal-title":"J Reprod Med"},{"key":"e_1_2_5_7_2","first-page":"32","article-title":"Precocious pseudo\u2010puberty in granulosa cell tumor in children less than 1 year old. 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