{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T18:29:02Z","timestamp":1773685742014,"version":"3.50.1"},"reference-count":31,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2009,5,20]],"date-time":"2009-05-20T00:00:00Z","timestamp":1242777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Post\u2010transplant lymphoproliferative disorder (PTLD) occasionally presents as Burkitt lymphoma\/L3 leukaemia (BLL).<\/jats:p><\/jats:sec><jats:sec><jats:title>Procedure<\/jats:title><jats:p>We reviewed records of cases of PTLD post\u2010cardiac transplantation (1990\u20132007) occurring in our unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were 15 episodes in 13 patients including four cases of EBV\u2010driven Burkitt\u2010type disease with t(8;14) translocations presenting with advanced stage disease. The first case was treated with a variety of low dose chemotherapy combinations. Despite problems during therapy he obtained complete remission, but died from complications of pre\u2010existing cardiac allograft vasculopathy 7 months later. The subsequent three cases were treated with a UKCCSG low stage lymphoma protocol, NHL 9001 and Rituximab. They remain in complete remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the context of PTLD the prognostic significance of advanced stage EBV\u2010driven BLL with the t(8;14) translocation may be different to that in immunocompetent children. Pediatr Blood Cancer 2009;53:392\u2013396. \u00a9 2009 Wiley\u2010Liss, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.22070","type":"journal-article","created":{"date-parts":[[2009,5,20]],"date-time":"2009-05-20T23:48:39Z","timestamp":1242863319000},"page":"392-396","source":"Crossref","is-referenced-by-count":17,"title":["Post cardiac transplantation lymphoproliferative disorder presenting as t(8;14) Burkitt leukaemia\/lymphoma treated with low intensity chemotherapy and rituximab"],"prefix":"10.1002","volume":"53","author":[{"given":"Kevin","family":"Windebank","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Walwyn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gareth","family":"Parry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asif","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Bown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bridget","family":"Wilkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,5,20]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)67933-6"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2005.05.038"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200101000-00005"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.11.3370"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.10.2392"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199905270-00017"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.318.7191.1113"},{"key":"e_1_2_4_9_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2003.04323.x"},{"key":"e_1_2_4_10_2","first-page":"106","article-title":"Malignant lymphomas in transplantation patients","volume":"1","author":"Penn I","year":"1969","journal-title":"Transplant Proc"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199904150-00010"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V86.9.3333.bloodjournal8693333"},{"key":"e_1_2_4_13_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V92.9.3137.421k28_3137_3147"},{"key":"e_1_2_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200101000-00003"},{"key":"e_1_2_4_15_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.08.074"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2004.12.124"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200110000-00012"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/11.suppl_1.S113"},{"key":"e_1_2_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2005.01098.x"},{"key":"e_1_2_4_20_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0377"},{"key":"e_1_2_4_21_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190600908349"},{"key":"e_1_2_4_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000295987.12996.19"},{"key":"e_1_2_4_23_2","first-page":"3945S","article-title":"A pilot study of chemoimmunotherapy (cyclophosphamide, prednisone, and rituximab) in patients with post\u2010transplant lymphoproliferative disorder following solid organ transplantation","volume":"9","author":"Orjuela M","year":"2003","journal-title":"Clin Cancer Res"},{"key":"e_1_2_4_24_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-007-0298-2"},{"key":"e_1_2_4_25_2","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.10595"},{"key":"e_1_2_4_26_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V92.5.1549"},{"key":"e_1_2_4_27_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-12-063008"},{"key":"e_1_2_4_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-911X(199609)27:3<156::AID-MPO4>3.0.CO;2-D"},{"key":"e_1_2_4_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200306000-00014"},{"key":"e_1_2_4_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0950-3536(05)80206-9"},{"key":"e_1_2_4_31_2","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2005.1.329"},{"key":"e_1_2_4_32_2","doi-asserted-by":"publisher","DOI":"10.5414\/NPP26068"}],"container-title":["Pediatric Blood &amp; 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