{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T02:58:21Z","timestamp":1761101901124},"reference-count":7,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,3,22]],"date-time":"2010-03-22T00:00:00Z","timestamp":1269216000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2010,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report a case of Peutz\u2013Jeghers syndrome (PJS) in a 2\u2010year old with precocious puberty secondary to a Sertoli\u2013Leydig cell tumour. Family history of PJS and other neoplasms were discovered. The tumour was excised and the STK11 gene deletion identified in both patient and father. Screening revealed hamartomatous gastric polyps, which were removed. Current recommendations for screening of children with PJS begin at age 8 years, based on reported occurrence of complications <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#bib1\">1<\/jats:ext-link>. This report illustrates the importance of considering early screening, along with close clinical review and patient\/parent education, for detection of life threatening neoplasms and complications. Pediatr Blood Cancer 2010;55:206\u2013207. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.22433","type":"journal-article","created":{"date-parts":[[2010,3,22]],"date-time":"2010-03-22T22:46:55Z","timestamp":1269298015000},"page":"206-207","source":"Crossref","is-referenced-by-count":13,"title":["Sertoli Leydig cell ovarian tumour and gastric polyps as presenting features of Peutz\u2013Jeghers syndrome"],"prefix":"10.1002","volume":"55","author":[{"given":"Lisa","family":"Howell","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulgader","family":"Bader","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhanya","family":"Mullassery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Losty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Auth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Kokai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3,22]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.2003.010900"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM194912292412601"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.20228"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.03.014"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3800311"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-0004.2007.00907.x"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.mph.0000188302.97324.6d"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22433","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22433","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.22433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T00:21:33Z","timestamp":1696724493000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.22433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,22]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,7,15]]}},"alternative-id":["10.1002\/pbc.22433"],"URL":"https:\/\/doi.org\/10.1002\/pbc.22433","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,22]]}}}