{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T01:00:46Z","timestamp":1776128446687,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,3,27]],"date-time":"2010-03-27T00:00:00Z","timestamp":1269648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2010,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Extranodal natural killer (NK)\/T\u2010cell lymphoma, nasal type, is a rare lymphoma that occurs predominantly in Asian adults. In this report, we describe the clinical and pathologic features of an unusual aggressive lymphoid neoplasm in a child and review the literature on NK\/T\u2010cell lymphoma in children. The patient was a 4\u2010year\u2010old Native American male with facial swelling, lymphadenopathy, and fevers. Biopsy demonstrated neoplastic lymphoid cells that expressed CD3, CD8, TIA\u20101, and EBV\u2010encoded RNA without CD56. The patient failed multiagent chemotherapy and died of therapy\u2010related complications. This case represents an extranodal NK\/T\u2010cell lymphoma, nasal type, with an unusual lack of CD56. Pediatr Blood Cancer 2010;55:186\u2013189. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.22489","type":"journal-article","created":{"date-parts":[[2010,3,27]],"date-time":"2010-03-27T23:02:41Z","timestamp":1269730961000},"page":"186-189","source":"Crossref","is-referenced-by-count":10,"title":["CD56\u2010negative extranodal nasal type NK\/T\u2010cell lymphoma"],"prefix":"10.1002","volume":"55","author":[{"given":"Rodney R.","family":"Miles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeinab","family":"Afify","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Yaish","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sherrie L.","family":"Perkins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,3,27]]},"reference":[{"key":"e_1_2_5_2_2","first-page":"285","volume-title":"WHO Classification of tumours of haematopoietic and lymphoid tissues","author":"Chan JKC","year":"2008"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2004.01867.x"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.12.4501"},{"key":"e_1_2_5_5_2","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1182\/blood.V89.11.3909","article-title":"A Clinical Evaluation of the International Lymphoma Study Group Classification of Non\u2010Hodgkin's Lymphoma","volume":"89","author":"The Non\u2010Hodgkin's Lymphoma Classification P","year":"1997","journal-title":"Blood"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-10-185256"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1997.1462962.x"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21543"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010215)91:4<642::AID-CNCR1047>3.0.CO;2-2"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199907083410204"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0936-6555(97)80081-7"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.2350\/06-07-0140.1"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22489","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.22489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T00:24:38Z","timestamp":1696724678000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.22489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3,27]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2010,7,15]]}},"alternative-id":["10.1002\/pbc.22489"],"URL":"https:\/\/doi.org\/10.1002\/pbc.22489","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3,27]]}}}