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Due to the paucity of information regarding successful treatment, we report the case of a 6 month old female referred for leukocoria and found to have an associated suprasellar tumor and pineal enhancement. The patient, treated with standard infant brain tumor therapy, remains alive without signs of active disease 35 months after diagnosis; no surgery or irradiation was used. Early diagnosis of trilateral retinoblastoma may facilitate the use of less intensive therapeutic approaches and result in excellent outcomes in these patients. Pediatr Blood Cancer. 2010;55:570\u2013572. \u00a9 2010 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.22545","type":"journal-article","created":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T00:14:19Z","timestamp":1274919259000},"page":"570-572","source":"Crossref","is-referenced-by-count":22,"title":["Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy"],"prefix":"10.1002","volume":"55","author":[{"given":"Karen D.","family":"Wright","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Qaddoumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zoltan","family":"Patay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amar","family":"Gajjar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew W.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Rodriguez\u2010Galindo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,7,19]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1999.17.6.1829"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197705)39:5<2048::AID-CNCR2820390522>3.0.CO;2-9"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)92009-7"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-4608(82)90026-7"},{"key":"e_1_2_6_6_2","first-page":"505","article-title":"Trilateral retinoblastoma: Clinical and radiological progression","volume":"183","author":"Provenzale JM","year":"2004","journal-title":"Am J Radiol"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.20464"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19910201)67:3<710::AID-CNCR2820670330>3.0.CO;2-3"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)90560-6"},{"key":"e_1_2_6_10_2","doi-asserted-by":"crossref","first-page":"26","DOI":"10.3928\/0191-3913-19940101-06","article-title":"Clinical variations of trilateral retinoblastoma: A report of 13 cases","volume":"31","author":"De Potter P","year":"1994","journal-title":"J Pediatr Ophthalmol Strabismus"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199306173282401"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/1.2.152"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.09.095"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1998.16.1.210"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3180308782"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990701)86:1<135::AID-CNCR19>3.0.CO;2-0"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960815)78:4<858::AID-CNCR24>3.0.CO;2-T"},{"key":"e_1_2_6_18_2","first-page":"1513","article-title":"Chemoreduction for retinoblastoma may prevent intracranial neuroblastic malignancy (trilateral retinoblastoma)","volume":"121","author":"Shields CL","year":"2003","journal-title":"Arch Ophthalmol"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20001115)89:10<2117::AID-CNCR12>3.0.CO;2-9"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.22336"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.10.096"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22545","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.22545","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T12:23:45Z","timestamp":1700569425000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.22545"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7,19]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,9]]}},"alternative-id":["10.1002\/pbc.22545"],"URL":"https:\/\/doi.org\/10.1002\/pbc.22545","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,7,19]]}}}