{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:04:49Z","timestamp":1785769489983,"version":"3.56.0"},"reference-count":17,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2011,2,10]],"date-time":"2011-02-10T00:00:00Z","timestamp":1297296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2011,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Wiskott\u2013Aldrich Syndrome (WAS) is a triad of immunodeficiency, eczema, and thrombocytopenia. Despite the heterogeneity of genetic and clinical findings, a correlation with small platelet size is routinely observed. Herein we describe a case with a unique phenotype that links normal mean platelet volume with the classic characteristics of this disease. The diagnosis was verified by genetic analysis showing a novel and de novo mutation. Our case illustrates that a high index of suspicion of WAS is warranted even in the setting of normal sized platelets. Pediatr Blood Cancer 2011;56:1127\u20131129. \u00a9 2011 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/pbc.22920","type":"journal-article","created":{"date-parts":[[2011,2,10]],"date-time":"2011-02-10T17:56:11Z","timestamp":1297360571000},"page":"1127-1129","source":"Crossref","is-referenced-by-count":21,"title":["A unique presentation of Wiskott\u2013Aldrich syndrome in relation to platelet size"],"prefix":"10.1002","volume":"56","author":[{"given":"Payal D.","family":"Patel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joy M.","family":"Samanich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William B.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa","family":"Manwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,2,10]]},"reference":[{"key":"e_1_2_4_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-12-115253"},{"key":"e_1_2_4_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e3282f30448"},{"key":"e_1_2_4_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-008-8084-3"},{"key":"e_1_2_4_5_2","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118712"},{"key":"e_1_2_4_6_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1592"},{"key":"e_1_2_4_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.75.5.436"},{"key":"e_1_2_4_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-008-8069-2"},{"key":"e_1_2_4_9_2","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1182\/blood.V65.6.1439.bloodjournal6561439","article-title":"Platelet\u2010associated immunoglobulin, platelet size, and the effect of splenectomy in the Wiskott\u2013Aldrich syndrome","volume":"65","author":"Corash L","year":"1985","journal-title":"Blood"},{"key":"e_1_2_4_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.1999.01637.x"},{"key":"e_1_2_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.imbio.2009.06.009"},{"key":"e_1_2_4_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1975.02120420058019"},{"key":"e_1_2_4_13_2","first-page":"74","article-title":"Acute immune complex mediated glomerulonephritis in a Chinese girl with Wiskott\u2013Aldrich syndrome variant","volume":"53","author":"Lin CY","year":"1984","journal-title":"Ann Allergy"},{"key":"e_1_2_4_14_2","first-page":"91","article-title":"Phagocyte function and immunological findings in a Wiskott\u2013Aldrich syndrome long\u2010term survivor","volume":"19","author":"Capsoni F","year":"1986","journal-title":"J Clin Lab Immunol"},{"key":"e_1_2_4_15_2","doi-asserted-by":"crossref","first-page":"4538","DOI":"10.1182\/blood.V87.11.4538.bloodjournal87114538","article-title":"Wiskott\u2013Aldrich syndrome: Report of an autosomal dominant variant","volume":"87","author":"Rocca B","year":"1996","journal-title":"Blood"},{"key":"e_1_2_4_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.30.11.968"},{"key":"e_1_2_4_17_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.6.1598"},{"key":"e_1_2_4_18_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-076679"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22920","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.22920","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.22920","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T23:53:35Z","timestamp":1697586815000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.22920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2,10]]},"references-count":17,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2011,7]]}},"alternative-id":["10.1002\/pbc.22920"],"URL":"https:\/\/doi.org\/10.1002\/pbc.22920","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718390785.793495357","asserted-by":"object"}]},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,2,10]]}}}