{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T15:36:25Z","timestamp":1790868985616,"version":"4.1.0"},"reference-count":20,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T00:00:00Z","timestamp":1332201600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Direcci\u00f3n de Investigaci\u00f3n, Hospital Infantil de M\u00e9xico Federico Gomez"},{"name":"The Kindercancer Foundation"},{"name":"Consejo Nacional de Ciencia y Tecnolog\u00eda (CONACYT), M\u00e9xico","award":["2007-1-71223\/FIS\/IMSS\/PROT\/592"],"award-info":[{"award-number":["2007-1-71223\/FIS\/IMSS\/PROT\/592"]}]},{"name":"Consejo Nacional de Ciencia y Tecnolog\u00eda (CONACYT), M\u00e9xico","award":["CB-2007-1-83949\/FIS\/IMSS\/PROT\/616"],"award-info":[{"award-number":["CB-2007-1-83949\/FIS\/IMSS\/PROT\/616"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2012,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Haploidentical hematopoietic cell transplantation using CD34<jats:sup>+<\/jats:sup> cells depleted of T lymphocytes by the CliniMACS is a treatment for hematological malignancy. We report on four Mexican children, three with acute lymphocytic leukemia and one with chronic myelocytic leukemia, who was transplanted with 12\u2009\u00d7\u200910<jats:sup>6<\/jats:sup>\u2009CD34<jats:sup>+<\/jats:sup>\u2009stem cells\/kg body weight (98% of purity) with a follow\u2010up of <jats:styled-content>$9{\\textstyle{{1} \\over {2}}}$<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/tex2gif-ueqn-1.gif\" xlink:title=\"equation image\"\/><\/jats:styled-content> years. The engraftment was successful in three of the four children. All showed cytomegalovirus reactivation, and one died because of graft rejection and infectious complication. The risk of infections was a major problem. Pediatr Blood Cancer 2012; 59: 950\u2013952. \u00a9 2012 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/pbc.24114","type":"journal-article","created":{"date-parts":[[2012,3,20]],"date-time":"2012-03-20T19:43:53Z","timestamp":1332272633000},"page":"950-952","source":"Crossref","is-referenced-by-count":3,"title":["Haploidentical bone marrow transplantation in Mexico"],"prefix":"10.1002","volume":"59","author":[{"given":"Jos\u00e9 Eugenio","family":"V\u00e1zquez\u2010Meraz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Arellano\u2010Galindo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emma","family":"Mendoza\u2010Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elva","family":"Jim\u00e9nez\u2010Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Armando Mart\u00ednez","family":"Avalos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norma Vel\u00e1zquez","family":"Guadarrama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Manuel Mej\u00eda","family":"Arangure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,3,20]]},"reference":[{"key":"e_1_2_6_2_2","first-page":"323","volume":"46","author":"Ballen K","year":"2011","journal-title":"The great debate: Haploidentical or cord blood transplant."},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-01-263657"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-04-1203"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3046.7.s3.7.x"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2010.10.024"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2009.252"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1386-6532(98)00046-4"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.5.1845-1853.2000"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701119"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12026-010-8191-9"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2010.06.019"},{"key":"e_1_2_6_13_2","doi-asserted-by":"crossref","first-page":"4226","DOI":"10.1182\/blood.V89.11.4226","article-title":"Transplantation of marrow cells from unrelated donors for treatment of high risk acute leukemia: The effect of leukemia burden, donor HLA\u2010matching, and marrow cell dose","volume":"89","author":"Sierra J","year":"1997","journal-title":"Blood"},{"key":"e_1_2_6_14_2","first-page":"5","article-title":"Transplantation of megadose of purified haploidentical stem cells","volume":"7","author":"Handgretinger R","year":"1999","journal-title":"Ann NY Acad Sci"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1702202"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2401577"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2004.08.008"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e3181cf813c"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2000.02359.x"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2009.189"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2008.120"}],"container-title":["Pediatric Blood &amp; 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