{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T06:56:19Z","timestamp":1786690579865,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T00:00:00Z","timestamp":1359936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Obstructive sleep apnea (OSA) in the pediatric sickle cell disease (SCD) population can promote nightly hemoglobin oxygen desaturation, which increases the risk of central nervous system insult and may impair cognitive function. Adenotonsillectomy can ameliorate OSA symptoms, but its effect in children with SCD has not been fully investigated. We reviewed the effects of adenotonsillectomy in thirteen children with SCD by comparison of pre and post\u2010adenotonsillectomy polysomnography (PSG) parameters. Significant reduction in hemoglobin oxygen desaturation, decreased apnea\u2010hypopnea index, and increased rapid eye movement sleep occurred after adenotonsillectomy. Adenotonsillectomy promotes improvement in sleep quality in children with SCD and PSG\u2010confirmed OSA. Pediatr Blood Cancer 2013; 60: E26\u2013E28. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/pbc.24479","type":"journal-article","created":{"date-parts":[[2013,2,4]],"date-time":"2013-02-04T16:19:25Z","timestamp":1359994765000},"source":"Crossref","is-referenced-by-count":23,"title":["Effects of adenotonsillectomy on polysomnographic parameters in children with sickle cell disease"],"prefix":"10.1002","volume":"60","author":[{"given":"Paul","family":"Finch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose Mary","family":"Stocks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew P.","family":"Smeltzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Kimble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Schoumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane S.","family":"Hankins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,2,4]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1392"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)04821-2"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1355617711001469"},{"key":"e_1_2_6_5_2","doi-asserted-by":"crossref","first-page":"3422","DOI":"10.1182\/blood.V81.12.3422.3422","article-title":"Pulse oximetry and factors associated with hemoglobin oxygen desaturation in children with sickle cell disease","volume":"81","author":"Rackoff WR","year":"1993","journal-title":"Blood"},{"key":"e_1_2_6_6_2","volume-title":"The International Classification of Sleep Disorders, Diagnostic and Coding Manual","year":"2001"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.111.964783"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-2089F"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.4.963"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.68.3.360"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/MPH.0b013e31817eb7ef"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1590\/S1806-37132009001100004"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2013"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2009.07652.x"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-010-1048-4"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-0823"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911800405"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2009.11.006"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.27880"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-010-0093-2"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.4067\/S0716-97602007000500008"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.24479","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.24479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T08:06:41Z","timestamp":1700640401000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.24479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2,4]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2013,7]]}},"alternative-id":["10.1002\/pbc.24479"],"URL":"https:\/\/doi.org\/10.1002\/pbc.24479","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2,4]]}}}