{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:23:50Z","timestamp":1788870230915,"version":"build-2803163510"},"reference-count":12,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T00:00:00Z","timestamp":1361750400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Parents' Association A.S.L.T.I.-Liberi di crescere Onlus"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2013,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Essential thrombocythemia (ET) is extremely rare in the pediatric population. In most patients no molecular abnormality can be found, with about 40% of pediatric patients harboring a JAK2 V617F mutation. Another recurrent mutation, involving a W to L or K transversion at MPL codon 515, has been reported in about 3\u20138% of adult ET patients. Herein we describe this mutation in a pediatric patient. Pediatr Blood Cancer 2013;60E52\u2010E54. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pbc.24500","type":"journal-article","created":{"date-parts":[[2013,2,25]],"date-time":"2013-02-25T12:12:28Z","timestamp":1361794348000},"source":"Crossref","is-referenced-by-count":11,"title":["MPL W515L mutation in pediatric essential thrombocythemia"],"prefix":"10.1002","volume":"60","author":[{"given":"Piero","family":"Farruggia","sequence":"first","affiliation":[{"name":"Oncology Department, Pediatric Hematology and Oncology Unit A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"D'Angelo","sequence":"additional","affiliation":[{"name":"Oncology Department, Pediatric Hematology and Oncology Unit A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"La Rosa","sequence":"additional","affiliation":[{"name":"Hematology I, A.O. Villa Sofia\u2010Cervello Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nunzia","family":"Scibetta","sequence":"additional","affiliation":[{"name":"Unit of Pathology A.R.N.A.S. Ospedali Civico, Di Cristina e Benfratelli Palermo Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Santangelo","sequence":"additional","affiliation":[{"name":"Child Neurology and Psychiatric Unit A.R.N.A.S. 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