{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T12:47:46Z","timestamp":1778935666206,"version":"3.51.4"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T00:00:00Z","timestamp":1387756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>To date ten sets of monozygotic twins with neuroblastoma have been reported in the literature. Twin\u2010to\u2010twin <jats:italic>in utero<\/jats:italic> metastasis have been proposed as the mechanism of tumor development in the second twin; based on similar pathology, presence of metastatic disease, absence of a primary tumor, and\/or later presentation in the second twin. Hereditary neuroblastoma has not been described in this context. We propose that primary neuroblastoma can occur in monozygotic twins without twin\u2013twin transmission; due to the different ages of presentation, histology, ploidy, and tumor behavior. Pediatr Blood Cancer 2014;61:1124\u20131125. \u00a9 2013 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.24906","type":"journal-article","created":{"date-parts":[[2013,12,23]],"date-time":"2013-12-23T11:43:16Z","timestamp":1387798996000},"page":"1124-1125","source":"Crossref","is-referenced-by-count":5,"title":["Neuroblastoma in monozygotic twins with distinct presentation pathology and outcome: Is it familial or <i>in utero<\/i> metastasis"],"prefix":"10.1002","volume":"61","author":[{"given":"Rolla","family":"Abu\u2010Arja","sequence":"first","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology and Bone Marrow Transplantation UH Rainbow Babies &amp; Children's Hospital\/Case Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Hashem","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology and Bone Marrow Transplantation UH Rainbow Babies &amp; Children's Hospital\/Case Medical Center Cleveland Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"El\u2010Sheikh","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology and Bone Marrow Transplantation Department of Pediatrics Carver College of Medicine University of Iowa Children's Hospital Iowa City Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghada","family":"Abusin","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology\u2010Oncology and Bone Marrow Transplantation Department of Pediatrics Carver College of Medicine University of Iowa Children's Hospital Iowa City Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,23]]},"reference":[{"key":"e_1_2_4_2_1","first-page":"24","volume-title":"Principles and practice of pediatric oncology","author":"Pizzo PA","year":"2010"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07261"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860501)57:9<1887::AID-CNCR2820570931>3.0.CO;2-7"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-199809000-00017"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(97)00265-7"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2012.05.002"},{"key":"e_1_2_4_8_1","first-page":"9","article-title":"Ectopic neuroblastoma in monozygotic twins with different ages of onset: Possible twin\u2010to\u2010twin metastasis in utero with distinct genetic alterations after birth","volume":"9","author":"Taketani T","year":"2013","journal-title":"J Pediatr Hematol Oncol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.08.025"},{"key":"e_1_2_4_10_1","first-page":"810","article-title":"Tumors in one of homologous twins; neuroblastoma; fibromyxosarcoma in infant negro twins","volume":"70","author":"Charache H","year":"1953","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1086\/383253"}],"container-title":["Pediatric Blood &amp; Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fpbc.24906","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pbc.24906","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T22:28:59Z","timestamp":1696458539000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/pbc.24906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,23]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1002\/pbc.24906"],"URL":"https:\/\/doi.org\/10.1002\/pbc.24906","archive":["Portico"],"relation":{},"ISSN":["1545-5009","1545-5017"],"issn-type":[{"value":"1545-5009","type":"print"},{"value":"1545-5017","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,12,23]]}}}