{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T06:12:37Z","timestamp":1696572757870},"reference-count":12,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T00:00:00Z","timestamp":1403568000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:label \/><jats:p>Acute megakaryoblastic leukemia (AMKL) is a relatively common type of acute myeloid leukemia in children. We describe two unusual cases of AMKL that by flow cytometry (FC) lacked expression of any commonly evaluated myeloid antigens. One case presented as a periorbital myeloid sarcoma and clinically was thought to be a solid tumor. In both cases, the leukemic blasts were variably positive for the megakaryocytic marker CD61. Cytogenetics confirmed the presence of the t(1;22) in one case. Cytogenetics and inclusion of megakaryocytic markers in FC panels when evaluating pediatric specimens is critical for appropriate diagnosis for myeloid antigen negative AMKL. Pediatr Blood Cancer 2014;61:2089\u20132091. \u00a9 2014 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.25103","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T15:58:45Z","timestamp":1403625525000},"page":"2089-2091","source":"Crossref","is-referenced-by-count":2,"title":["Pan myeloid antigen\u2010negative pediatric acute megakaryoblastic leukemia"],"prefix":"10.1002","volume":"61","author":[{"given":"Neslihan","family":"Cetin","sequence":"first","affiliation":[{"name":"Department of Pathology Arkansas Children's Hospital and the University of Arkansas for Medical Sciences Little Rock Arkansas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert B.","family":"Lorsbach","sequence":"additional","affiliation":[{"name":"Department of Pathology Arkansas Children's Hospital and the University of Arkansas for Medical Sciences Little Rock Arkansas"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,6,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.12.3727"},{"key":"e_1_2_5_3_1","doi-asserted-by":"crossref","first-page":"1932","DOI":"10.1182\/blood.V75.10.1932.1932","article-title":"Identification of two risk groups in childhood acute myelogenous leukemia after therapy intensification in study AML\u2010BFM\u201083 as compared with study AML\u2010BFM\u201078. 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