{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T15:23:38Z","timestamp":1764689018907},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T00:00:00Z","timestamp":1422403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatric Blood &amp; Cancer"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:sec><jats:label \/><jats:p>Few patients in remission of Ph\u2010positive chronic myelogenous leukemia (CML) develop Ph\u2010negative MDS\/AML, usually with clonal cytogenetic abnormalities. Isolated Ph\u2010negative myeloid sarcoma (MS) is presented here as a form of such disorder, different from Ph\u2010positive MS establishing CML relapse in blastic phase. We describe 11\u2010year\u2010old male who developed Ph\u2010negative isolated MS with <jats:italic>NPM1<\/jats:italic> mutation, remaining in complete molecular remission of Ph\u2010positive chronic myeloid leukemia treated with allo\u2010HSCT in first chronic phase and with imatinib and donor lymphocyte infusion in molecular relapse. The possible mechanisms of the tumor formation are reviewed with stress on importance of comprehensive molecular\/cytogenetic evaluations. Pediatr Blood Cancer 2015;62:1070\u20131071. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p><\/jats:sec>","DOI":"10.1002\/pbc.25428","type":"journal-article","created":{"date-parts":[[2015,1,28]],"date-time":"2015-01-28T17:15:21Z","timestamp":1422465321000},"page":"1070-1071","source":"Crossref","is-referenced-by-count":3,"title":["Ph\u2010negative isolated myeloid sarcoma with <i>NPM1<\/i> gene mutation in adolescent with Ph\u2010positive chronic myeloid leukemia in remission after treatment with allogeneic bone marrow transplantation and imatinib mesylate"],"prefix":"10.1002","volume":"62","author":[{"given":"Jolanta","family":"Skalska\u2010Sadowska","sequence":"first","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danuta","family":"Januszkiewicz\u2010Lewandowska","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"},{"name":"Institute of Human Genetics Polish Academy of Sciences Pozna\u0144 Poland"},{"name":"Department of Medical Diagnostics Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katarzyna","family":"Derwich","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Pieczonka","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Samborska","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacek","family":"Wachowiak","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hematology Oncology and Transplantology University of Medical Sciences Pozna\u0144 Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1,28]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28012"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190290012056"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10428190902755513"},{"key":"e_1_2_3_5_1","first-page":"801","article-title":"Granulocytic sarcoma after allogeneic bone marrow transplantation: A retrospective European multicenter survey. 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